20th notebook by Dr Sourabh Kulkarni

*PYQ CORNER 04- [ONE QUESTION A DAY - DIRECT REPEAT FROM OUR NOTES]* FMGE JUNE 2025 (Strike rate - 235/300) Breastfed infant presents with Lethargy, hepatomegaly and cataract. Enzyme deficient? 1. Galactokinase 2. GALPUT 3. Aldolase B 4. ⁠Fructokinase Breastfed 2 month infant presents with vomiting and lethargy. Lab - Hyperammonemia & increased Orotic acid in urine. Enzyme deficient? 1. Carbamoyl phosphate synthase deficiency 2. OTC Deficiency 3. O-5-PD deficiency 4. Arginosuccinate lyase deficiency IMPORTANCE - 2 questions from this table in FMGE 2025 and over 5 questions in past year in all exams combined. Must read table (V2 Page 59)

*PYQ CORNER 03- [ONE QUESTION A DAY - DIRECT REPEAT FROM OUR NOTES]* FMGE JAN 2025 (Strike rate - 248/300) Mutation in KATG gene leading to ATT resistance is a/w which of the following drugs? 1. Isoniazid 2. Ethambutol 3. Rifampicin 4. ⁠Levofloxacin IMPORTANCE - Drug resistance table has been coded BLUE and we have already seen 3 questions in NEET/FMGE/INI in last 2 years from this table

*PYQ CORNER 02 - [ONE QUESTION A DAY - DIRECT REPEAT FROM OUR NOTES]* NEET 2025- A 65 year old man with fractured arm presents with bleeding of gums, perifollicular Hemorrhage. Which of the following enzymes is deficient in this man? Prolyl hydroxylase ALA Synthase Glutathione reductase Galactosyl transferase IMPORTANCE - The only highlighted part of the Amino Acid Metabolism table was a direct repeat.

*PYQ CORNER 01- [ONE QUESTION A DAY - DIRECT REPEAT FROM OUR NOTES]* INI NOVEMBER 2024 - 6*4 cm mass, Nipple discharge + invasion of PMajor Level I + II LN No mets. TNM Staging? Importance- Only TNM staging colour coded Blue (Category II) in our notes directly asked in exam.

Winner of episode 01. Stay tuned for next episode on Sunday 12 pm

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The contest begins tomorrow

*We are happy to announce our new contest Snap Connection - Decode the medical motif’* Few rules 1. 3-5 individual images will be posted every week that have to be independently identified 2. ⁠There will be a common connection between all the images that has to be decoded. 3. Individual images and the connection between them has to be answered in 24hours 4. ⁠The contest will run for 25 weeks for next 6 months. Questions will be posted on our YouTube channel and in Instagram page 5. ⁠Students getting all the individual images correct and the connection correct too will be considered for availing discount 6. ⁠One student will be awarded Rs 500 discount voucher can be availed on our 20th notebook. Upto Rs 300 can be availed on our upcoming product Flowchart booklet or on either of the volumes 7. ⁠One student can only win the contest once 8. ⁠The discount voucher is non transferable 9. ⁠After announcing the social media username of the winner in our WhatsApp group, student should text us within 24 hours. The voucher can be availed within 7 days of winning the contest. 10. ⁠Students getting the highest number of correct answers at the end of the contest will get both volumes of 20th notebook or our other products free of cost. 11. ⁠ There might be few questions that may have another relevant connection than the one intended to be by the author. Relevance of the connection will be established by our team after explanation and decision will be final.

#Session2 Day25

#Session2 Day 24 Beta HCG in pregnancy