خلاصة المرحلة الرابعة

المحاضرة مشخبطة

🟣روابط الشرح مواد مرحلة الرابعة 🔸قناة دكتور أحمد هاشمي (شرح صناعية) 🔸قناة مثل حبة (شرح صناعية+كيمياء كورس اول) 🔷قناة تلي لطالب يشرح بايوفارمسي 🔸قناة دكتور احمد المحمدي (شرح بايوفارمسي) 🔸قناة دكتور طارق(يشرح فارما بشكل حلو ويفهم) 🔸قناة دكتور عبد المتعال(فارما) 🔷قناة تلي لطالب محمد شارح كيمياء الكورسين 🔸قناة مهارات التوصل دكتور مصطفى شرح ممتع جدًا ومفيد 🔸قناة دكتور محمد الركابي شارح سريرية 🔷ملازم سريرية بشكل مرتب كورس ثاني

سؤال مد 🔴🔴🔴🔴 What are the main differences between passive and active transport mechanisms of drug passage across the cell membrane and what do you think is the most important one?

سؤال مد 🔴🔴🔴🔴 What is Fick’s law of diffusion and what are the main factors that affect the rate of diffusion?

سؤال مد 🔴🔴🔴🔴 All new drugs and vaccines (including COVID-19 Vaccine) must pass stringent phases prior to marketing, why? And briefly explain these phases. Because any drug must pass through these stringent pleases in order to ensure that drug is effective and without any fatal side effects •Pre-clinical testing: A study to test a drug, a procedure, or another medical treatment in animals. The aim of a preclinical study is to collect data in support of the safety of the new treatment. Preclinical studies are required before clinical trials in humans can be started. •Clinical trials: Testing of the desired pharmacological effects in human population through controlled phases of clinical trials •Post-marketing studies: means any clinical trials or studies conducted with a Licensed Product after receipt of Regulatory Approval of the Licensed Product, which are conducted voluntarily in order to enhance marketing or scientific knowledge of the Licensed Product and are not required by Regulatory Authorities or are not intended to support Regulatory Approval of a Licensed Product for a new indication or other material change to the Product Label and Insert.

سؤال مد 🔴🔴🔴🔴 All drugs administered rectally bypass the first pass metabolism. True or false with explanation.

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سؤال مد 🔴🔴🔴🔴 Why griseofulvin is better absorbed in fatty meal? Because the drug is high lipid soluble and need for a surfactant (bile) to increase their solubility in the aqueous environment of the small intestine, and this surfactant secreted only when high fatty meal presence in the small intestine, so this dug should be taken with high fatty meal to dissolution in the small intestine

سؤال مد 🔴🔴🔴🔴🔴 Some diseases of the endocrine glands can affect drug absorption. Explain with examples.