Important knowledge

Fanconi anemia

⚡️Treatment Cold type - avoid cold temperatures - Plasmapheresis Warm type - corticosteroids - Splenectomy (غير فعالات بال cold type)

Cold type ⬆️ MCV , MCHC direct antiglobulin ( Coombs’ ) test + Warm type ⬆️ MCV direct antiglobulin ( Coombs’ ) test + (in 95%) (the most important diagnostic test ) indirect antiglobulin ( Coombs’ ) test + (in 80%) In both ⬆️ reticulocyte ⬇️ hemoglobin ⬆️ bilirubin

For acquired immune hemolytic anemia the most important is : Cold = IgM Warm = IgG ( ال IgG عدنا ال G يعني جهنم حار يعني warm )

⚡️dupuytren's contracture Causes ▪︎alcoholism ▪︎DM ▪︎Epilepsy

سوالف يحبها ويسال بيها د محمد عبدالله بما انو باجر يمتحن 😁

bacillus cereus=بالهستري ماكلين تمن بايت clostridium perfringens=بالهستري ماكلين بركر campylobacter=تسوي guillain barre enterohaemorrhagic e coli =don't give AB it will cause release of enterotoxin and cause hemolytic uremic syndrome clostridium difficile =hx of taking Ab علاجها 1st line metronidazole 500mg for 10 days second is vancomycin 125mg 4time daily for 10days clostridium botulism = cause diplopia نلكاها بالمواد المعلبه from dr mohammed abdullah

The apple maggot (Rhagoletis pomonella), also known as the railroad worm is a species of fruit fly, and a pest of several types of fruits, especially apples اليوم سأل بيها محمد عبد الله 😅 لا تتوتر ابني بس اني حظك :

⚡️Effects of breathing on heart rate & pulse volume ------------------ ▪︎HR ⬆️ with inspiration & ⬇️ with expiration ▪︎pulse volume ⬇️ with inspiration & ⬆️ with expiration

⚡️most common site for extranodal non-Hodgkin lymphoma is stomach

⚡️celiac serology ▪︎Anti - TTG antibodies (IgA ) هذا ال IgG مالته ميفيد طالع صاعد نازل ميعني شي ومنعتمد عليه ▪︎Anti-endomysial antibodies (IgA ) ذني ندز وياهن (IgA level) اذا طلع المريض عندة IgA deficiency فافضل فحص اله هو ▪︎De-amelated gliden peptide IgG

⚡️Splenic atrophy caused by : ▪︎celiac disease ▪︎sickle cell anemia

مقدسات محمد عبدالله

⚡️ECG finding of pericarditis ------------‐------------‐----------------‐‐-‐- ▪︎widespread ST elevation with upward concavity ▪︎PR interval depression ( very specific) ▪︎T-wave inversion (late,if there is a degree of myocarditis)

Infective endocarditis Osler node = painful/vasculitis Janeway lesion = painless/ immune mediated

⚡️Patients who are found to have endocarditis caused by Strep. gallolyticus should undergo colonoscopy (Because this organism is associated with large-bowel malignancy.)

⚡️The most commonly affected valve in rheumatic heart disease is mitral valve