Pharma/Clinical/Therapeutics

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حلول GBT 1. b) Uniform distribution of ingredients 2. c) Hammer milling 3. b) Freeze drying (lyophilization) 4. b) Separate suspended solids from liquids 5. b) V-blender 6. b) Jet mill 7. e) All of the above 8. c) Membrane filtration 9. b) Segregation 10. b) Impact and attrition 11. b) Sublimation of ice under vacuum 12. b) Sterilizes without heat 13. c) Speed of impeller 14. c) Difficulty in drying 15. c) Tray drying 16. b) Particle retention size 17. c) Tablets 18. c) Autoclaving 19. c) Temperature 20. b) Membrane filte 21. b) Proper blending time 22. b) Convert liquid formulations into dry powders 23. c) Microbial contamination 24. b) Jet mill 25. b) Destroy all forms of microbial life 26. c) High shear mixer 27. b) Requires long exposure time ppharma9 28. b) Jet mill 29. a) Reduce vortex formation 30. c) Filter clogging 31. d) Parenteral injections 32. a) Compression 33. d) Freeze drying 34. b) Air collisions at high velocity 35. b) 121°C, 15 psi, 15–20 min 36. c) V-blender mixing 37. b) Differences in particle size and density 38. c) Ethylene oxide gas 39. c) Particle color 40. c) Reduce particle size 41. c) Avoid irritation and infection 42. c) Homogenizing dry powders 43. c) Remove microbial contaminants from air https://t.me/ppharma9 44. c) Improper filter integrity testing 45. c) Autoclaving 46. c) Bulk powder production 47. a) Reducing temperature 48. d) They require aseptic handling and packaging 49. c) Heat generation can degrade the product 50. b) Mixing https://t.me/ppharma9

48. Which of the following statements is true regarding sterile products? a) They can contain limited microbial load b) They must be preserved with alcohol c) They are not affected by air contamination d) They require aseptic handling and packaging e) They are always heat sterilized 49. What is the risk if milling is not controlled properly? a) Powder becomes sterile b) Particle size becomes uniform c) Heat generation can degrade the product d) Moisture content is reduced e) No change in product quality 50. Which process is often used before tablet compression? a) Lyophilization b) Mixing c) Sterilization d) Filtration e) Coating مهمات ضروري حلوها https://t.me/ppharma9

24. Which equipment is best for particle size reduction of heat-sensitive materials? a) Hammer mill b) Jet mill c) Ball mill d) Roller mill e) Cutter mill 25. The main objective of sterilization is to: a) Improve solubility b) Destroy all forms of microbial life c) Increase drug stability d) Improve tablet hardness e) Enhance color uniformity 26. Which mixing equipment is ideal for cohesive powders? a) V-blender b) Paddle mixer c) High shear mixer d) Ribbon blender e) Turbine mixer 27. What is a major limitation of dry heat sterilization? a) Cannot sterilize metal instruments b) Requires long exposure time c) High moisture requirement d) Incomplete spore destruction e) Changes in pH of product 28. Which milling method provides the narrowest particle size distribution? a) Cutter mill b) Jet mill c) Hammer mill d) Ball mill e) Roller mill 29. What is the role of a baffle in a mixing tank? a) Reduce vortex formation b) Increase particle size c) Improve heating d) Dry the mixture e) Add ingredients continuously 30. A major drawback of filtration sterilization is: a) High heat exposure b) Loss of volatiles c) Filter clogging d) Slow drying e) Color change 31. Which product must always be sterilized before administration? a) Syrups b) Tablets c) Ointments d) Parenteral injections e) Capsules 32. What is the typical final step after wet granulation and drying? a) Compression b) Milling c) Filtration d) Blending e) Coating 33. Which drying method produces a porous and brittle product ideal for reconstitution? a) Oven drying b) Vacuum drying c) Spray drying d) Freeze drying e) Tray drying 34. During jet milling, particles are reduced in size by: a) Mechanical shear b) Air collisions at high velocity c) Cutting with blades d) Heating and pressing e) Stirring at high speeds 35. In autoclave sterilization, what conditions are typically used? a) 160°C for 2 hours b) 121°C, 15 psi, 15–20 min c) 80°C for 30 minutes d) 180°C, dry heat e) 100°C, atmospheric pressure 36. Which mixing technique relies on tumbling motion? a) Paddle mixing b) High shear mixing c) V-blender mixing d) Ultrasonic mixing e) Magnetic stirring 37. What causes segregation after mixing is completed? a) Excess binder b) Differences in particle size and density c) Freeze drying d) Low pH e) Over-drying 38. Which is the most suitable sterilization method for plastic syringes? a) Autoclaving b) Dry heat c) Ethylene oxide gas d) Gamma radiation e) Filtration 39. Which factor does not significantly affect drying efficiency? a) Surface area b) Airflow c) Particle color d) Temperature e) Humidity 40. Milling is performed in pharmaceutical manufacturing primarily to: a) Remove moisture b) Kill microorganisms c) Reduce particle size d) Improve compressibility e) Control viscosity 41. What is the main reason for sterilizing ophthalmic preparations? a) Extend shelf life b) Prevent fungal contamination c) Avoid irritation and infection d) Improve taste e) Reduce viscosity 42. Ribbon blenders are most commonly used for: a) High-shear mixing b) Solid-liquid blending c) Homogenizing dry powders d) Size reduction e) Wet granulation 43. What is the function of a HEPA filter in sterile rooms? a) Control temperature b) Maintain humidity c) Remove microbial contaminants from air d) Stabilize pressure e) Monitor airflow 44. Which factor increases the risk of contamination during filtration? a) Sterile handling b) Use of pre-filters c) Improper filter integrity testing d) Laminar flow hoods e) Closed filtration system https://t.me/ppharma9 45. Which of the following is a thermal sterilization method? a) Ethylene oxide b) Gamma radiation c) Autoclaving d) Membrane filtration e) UV light 46. Spray drying is most suitable for: a) Heat-labile injectables b) Lyophilized eye drops c) Bulk powder production d) Creams and ointments e) Capsule shells 47. Jet milling is preferred over hammer milling for: a) Reducing temperature b) High capacity output c) Crushing granules d) Producing large particles e) Agglomerating powders https://t.me/ppharma9

Pharmacy planet 🌍: 1. What is the main goal of mixing pharmaceutical powders? a) Increase particle size b) Uniform distribution of ingredients c) Enhance solubility d) Reduce moisture content e) Improve color uniformity 2. Which milling technique uses impact forces to reduce particle size? a) Ball milling b) Jet milling c) Hammer milling d) Roller milling e) Cutting milling 3. Drying by which method is most suitable for heat-sensitive materials? a) Spray drying b) Freeze drying (lyophilization) c) Oven drying d) Tray drying e) Vacuum drying 4. Filtration in pharmaceutical manufacturing is primarily used to: a) Remove dissolved substances b) Separate suspended solids from liquids c) Sterilize liquids d) Increase particle size e) Dry powders 5. What type of mixer is preferred for blending powders with minimal particle size change? a) High shear mixer b) V-blender c) Planetary mixer d) Paddle mixer e) Ribbon blender 6. Which milling equipment is commonly used for producing very fine powders? a) Hammer mill b) Jet mill c) Ball mill d) Roller mill e) Cutting mill 7. What factor most affects drying rate in a pharmaceutical drying process? a) Air temperature b) Air humidity c) Particle size d) Drying time e) All of the above 8. Which type of filtration is suitable for sterilizing heat-sensitive liquids? a) Gravity filtration b) Vacuum filtration c) Membrane filtration d) Centrifugation e) Filtration through filter paper 9. Over-mixing powders can cause: a) Improved flowability b) Segregation c) Particle size enlargement d) Reduced content uniformity e) Decreased moisture content 10. What is the main mechanism of jet milling? a) Compression b) Impact and attrition c) Shear d) Cutting e) Grinding 11. Freeze drying (lyophilization) removes moisture by: a) Evaporation under heat b) Sublimation of ice under vacuum c) Absorption by desiccants d) Centrifugation e) Filtration 12. What is the main advantage of membrane filtration? a) Removes dissolved gases b) Sterilizes without heat c) Removes large particles only d) Improves powder flow e) Reduces particle size 13. Which parameter is most important to control in high shear mixers? a) Mixing time b) Temperature c) Speed of impeller d) Humidity e) Particle shape 14. What is the main disadvantage of wet milling? a) High energy consumption b) Risk of contamination c) Difficulty in drying d) Poor size reduction e) Excessive heat generation 15. Which drying method uses heated air blown over the material to remove moisture? a) Freeze drying b) Spray drying c) Tray drying d) Vacuum drying e) Lyophilization 16. In pharmaceutical filtration, what does a filter’s pore size determine? a) Flow rate b) Particle retention size c) Filter material d) Temperature resistance e) Chemical compatibility 17. Which of the following is NOT a sterile product? a) Injectable solutions b) Ophthalmic solutions c) Tablets d) Inhalation aerosols e) Surgical implants 18. Which sterilization method uses moist heat? a) Dry heat sterilization b) Ethylene oxide sterilization c) Autoclaving d) Radiation sterilization e) Filtration sterilization 19. What is a critical parameter to monitor during milling to prevent overheating? a) Mill speed b) Feed rate c) Temperature d) Particle size e) Noise level 20. What type of filter is typically used for sterilizing pharmaceutical liquids? a) Depth filter b) Membrane filter c) Candle filter d) Plate filter e) Rotary filter 21. Which process is essential to ensure content uniformity in powder mixing? a) Overdrying b) Proper blending time c) Particle size enlargement d) Excessive milling e) Segregation 22. Spray drying is commonly used to: a) Reduce particle size of dry powders b) Convert liquid formulations into dry powders c) Sterilize liquids d) Remove large particles e) Filter liquids 23. What is the main risk during filtration of sterile products? a) Particle contamination b) Loss of active ingredients c) Microbial contamination d) pH changes e) Temperature fluctuations

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