Neurology

Figure 2 https://www.ncbi.nlm.nih.gov/core/lw/2.0/html/tileshop_pmc/tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&p=PMC3&id=11785518_cureus-0017-00000076749-i02.jpg

Variants of CIDP: clinical and electrophysiological hallmarks of CIDP subtypes. Motor deficits are drawn in red, sensory deficits in green and sensorimotor in brown colour. Classical CIDP presents often with proximal and distal sensorimotor deficits. Demyelination should be present as defined by the the EFNS/PNS criteria.1 ‘Distal acquired demyelinating symmetric neuropathy’ (DADS) shows typically distal symmetrical, sensory or sensorimotor symptoms and is often associated with abnormally increased distal motor latencies (dmL). Patients with Lewis-Sumner syndrome (LSS) display multifocal distributed sensory and motor symptoms, and nerve conduction studies frequently show conduction blocks. Pure sensory and motor CIDP show exclusively sensory or motor deficits and may have normal respective nerve conduction studies. Chronic immune sensory polyradiculopathy (CISP) is restricted to sensory nerve roots only (after ref 11). CANOMAD (chronic ataxic neuropathy associated with ophthalmoplegia, IgM paraprotein, cold agglutinins and disialosyl antibodies) presents as chronic ataxic neuropathy associated with oculomotor and/or bulbar symptoms. CIDP, chronic inflammatory demyelinating polyneuropathy; EFNS/PNS, European Federation of Neurological Societies and the Peripheral Nerve Society;NCV, nerve conduction velocity. https://jnnp.bmj.com/content/jnnp/90/9/981/F1.large.jpg?width=800&height=600&carousel=1

Proximal SMA, Zolgensma

Recent Advances in Therapy for the Neurodegenerative Disorder Ataxia-Telangiectasia https://www.mdpi.com/1422-0067/27/16/7347

Edaravone

Edaravone

Clinical presentation of ALS

Episodic ataxia type 1