𝒔𝒂𝒕𝒊𝒔𝒇𝒂𝒄𝒕𝒐𝒓𝒚 𝒂𝒏𝒂𝒍𝒚𝒛𝒆𝒔🔩

هنيالك ما عندك امتحانات👍💔

إذا اجه بالسؤال للسهوله TH1 = Crohn's disease (Macrophage) TH2 =Ulcerative colitis مهمه

تلخيص مكان الإصابة RA👉synovial membranes articular structures SLE👉intracellular particles in nucleic acids and nucleic acid binding proteins SpA👉spinal and peripheral joint oligoarthritis PA👉skin psoriasis .osteolysis and bony proliferation SS👉exocrine organs lacrimal and salivary glands Behcet👉inflammation of blood vessels CD👉small intestine Ileocolic Crohn's👉both the ileum Crohn's ileitis👉ileum only Crohn's colitis👉large intestine Ulcerative colitis👉colon and affects the mucosal layer only. AIH👉the liver PBC👉intrahepatic bile duct epithelium

🟣ملخص كل مرض ونوع الجين مالته 🟣كل مرض وياهي الHLA مالته

SLE SS PBC ر9:1ن Hepatitis B'C همات 9:1 بس بالرجال 9ينصابون ومريه وحده يعني ن9:1ر

RA = igM عالي SLE= igG عالي As= igA عالي Eczema = igE عالي Warm AIHA= IgG COLD AIHA = IgM 3 من ذن يجنكم وزاريات .✅️

طلاب انتبهوا المعيار الذهبي الي هو gold standard موجود بالمحاضره 6 مال CD ♦️EMAs:--->gold standard" for CD 👈هذا الفحص يعتبر المعيار الذهبي للCD وموجود بمحاضره حساسيه 21 6)The oral food challenge (OFC) 🟣ماهو اختبار OFC ♦️gold standard for diagnosis food allergy. 👈هالاختبار يعتبر مقياس ذهبي لتشخيص حساسية الطعام #مهـــمـــــه_كــــلــــش 3)patch test 🟣اختبار البقعة ♦️gold standard for---->contact dermatitis. 👈هذا الاختبار يعتبر مقياس ذهبي لألتهاب الجلد المتلامس #مهـــمـــــه_كــــلــــش ركزوو

نص ساعه علمود تصفن براحتك😂👍

تمديد وقت الامتحان التقويمي وجعله 3 ساعات ونصف بدلا من 3 ساعات توضيح / اضافة نصف ساعة للامتحان التقويمي للتحليلات المرضية

‏يارب فوّضت أمري إليك، أنت المُيسر وأنت المُسهّل يارب سهّل عليَّ ما أستصعبه وأجعل لي من توفيقك نصيب♥️ صباحكم الله بالخير

اي شي عدكم يخص كلية المصطفى او الفرات او الكوفه دزو ضروري✅👍

🔴محاضرة Behcet's Disease 🔵هذا المرض يصيب الرجال Men 🔸characterized by a triad of symptoms, including 🔹aphthous ulceration of the oral 🔹mucous membranes 🔹genitalia and uveitis 🔸Rare manifestations include 🔹oligoarthritis of the lower extremities 🔹vasculitis of the pulmonary vessels 🔹cerebrovascular symptoms 🔸Behcet's Disease associated with 🔹HLA B51 🔸Behcet's disease may cause inflammation called uveitis that means: 🔹Inflammation in the eyes 🔸Risk factors 🔹Age 🔹Geography 🔹Sex 🔹Genes 🔴مستويات التاليه كلها مرتفعه في مرض بهجت 🔹C-reactive protein levels 🔹erythrocyte sedimentation rate (ESR) 🔹leukocyte count 🔹complement components 🔸International Clinical Criteria for Behcet's Disease المعاییر السریریة الدولیة لمرض بھجت 🔹Recurrent oral ulcerations (apthous or herpetiform) 🔹Recurrent genital ulcerations 🔹Eye lesions (uveitis or retinal vasculitis 🔹Skin lesions (rashes or acne-like sores) 🔹Positive pathergy test

محاضرة Sjögren’s syndrome (SS) 🔹characterized by lymphatic infiltrates in exocrine organs (lacrimal and salivary glands) 🔹effects females (female:male ratio 9:1) ميزه اساسيه feature of SS i🔸 🔹deficient tear and saliva production due to lymphocytic xerostomia (dry mouth) and xerophthalmia (dry eyes) 🔸There are two type of Sjögren’s syndrome 🔹Primary Sjögren’s syndrome (when the disease occurs alone) 🔹Secondary Sjögren’s syndrome autoimmune diseases such as RA, SLE, Scleroderma, and polyarteritis nodosa. 🔹Schirmer’s test: to quantify the amount of tear production 🔸autoantibodies may have a role in Sjogren’s disease activity 🔹Anti-Ro (SSA) antibodies 🔸autoantibodies is considered specific for Sjögren's Syndrome 🔹Anti-La (SSB) antibody 🔸immunoglobulin is often elevated in the serum of patients with Sjögren's Syndrome 🔹lgA 🔸A number of factors play a role in the development of Sjögren’s syndrome یلعب عدد من العوامل دو ًرا في تطور متلازمة سجوجرن 🔹Endogenous factors [HLA-B*8-DRB1*03 ((B8 DR3) and hormones (estrogens) 🔹Exogenous factors [viruses (herpes and retrovirus)]

محاضره Ankylosing spondylitis اسماء الاخرى 🔹spondyloarthritis (SpA) 🔹spondyloarthropathy 🔸Ankylosing spondylitis is an inflammatory disease that usually affects: 🔹Spine 🔸is more commonly affected by ankylosing spondylitis 🔹Men الرجال 🔸blood test which is used to assess the tendency to develop ankylosing spondylitis 🔹(HLA)-B27 🔴A physical examinationthe Schober's test مرضئ الذين يعانون من AS يرتفع كل من 👇 🔹elevated levels of IgA 🔹elevated erythrocyte 🔹sedimentation rates 🔹C-reactive protein 🔵 بشكل شائع يرتفع ESR RF and ANA 👉👉👉negative ____________________________________ 🔸Psoriatic Arthritis 🔹characterized by osteolysis and bony proliferation يصيب الرجال ونساء 🔹Males and females are equally RF and ACPA 👉👉👉negative 🔴ايضا في هذا المرض ESR مرتفع Clinical manifestations include 🔹skin and nail psoriasis 🔹dactylitis 🔹enthesitis 🔹osteoperiostitis 🔹large joint oligoarthritis 🔹arthritis mutilans 🔹sacroiliitis 🔹spondylitis 🔹distal interphalangeal arthritis العوامل مصاحبه لمرضى التهاب المفاصل الصدفي Comorbidities in PsA PatientsPSA 🔹Ocular inflammation (Iritis Uveitis/ Episcleritis) 🔹Irritable bowel disease (IBD) 🔹Metabolic Syndrome (Hyperlipidemia, Hypertension, Insulin resistant , Diabetes ,Obesity ) lead to Higher risk of Cardiovascular disease (CVD) 🔹Psychosocial burden, Reactive depression, Higher suicidal ideation and Alcoholism

🔴محاضرة RA 🔸RA onset usually occur 🔹Between ages of 35-60 years 🔸is the main genetic risk factor for RA 🔹HLA-DR4 / HLA-DR1 🔸is the sex predilection ratio of RA 🔹Women: Men - 3:1 🔸is the most specific test for RA 🔹anti-CCP 🔸test is not very specific of Rheumatoid Arthritis 🔹Rheumatoid factor ( RF ) 🔸is elevated in approximately 90% of patient with RA 🔹ESR 🔸approximately 30% of patient with RAThis test is not routinely 🔹ANA 🔸test can be used to aid in the diagnosis of Rheumatoid arthritis: 🔹Anti-cyclic citrullinated peptide 🔹Rheumatoid factor 🔹ESR 🔹Blood test