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📘Multiple Choice History Questions 1. Who was known as the "Lion of Judah"? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Haile Selassie I 2. Which emperor defeated the Italians at the Battle of Adwa? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Lij Iyasu 3. Who established the first modern school system in Ethiopia? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Ezana 4. Which emperor attempted to modernize Ethiopia through reforms but faced resistance from the nobility? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Dawit III 5. Who expanded the Ethiopian empire to its greatest extent? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Zara Yaqob 6. Which emperor was known for his religious tolerance? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Susenyos I 7. Who defeated the Mahdist forces at the Battle of Gallabat? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Tekle Giyorgis II 8. Which emperor introduced the Gregorian calendar to Ethiopia? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Haile Selassie I 9. Who was the first Ethiopian emperor to visit Europe? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Lij Kassa 10. Which emperor was overthrown by a coup d'état in 1974? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Haile Selassie I 11. Who was known as the "Father of Modern Ethiopia"? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Justinian 12. Which emperor established the Ethiopian Orthodox Tewahedo Church? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Ezana 13. Who defeated the Egyptians at the Battle of Gura? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Bazen 14. Which emperor was known for his cruelty and paranoia? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Zara Yaqob 15. Who was the first Ethiopian emperor to establish a standing army? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Susenyos I 16. Which emperor introduced the first printing press to Ethiopia? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Yohannes IV 17. Who defeated the Italians at the Battle of Dogali? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Ras Alula 18. Which emperor was known for his diplomatic skills and ability to forge alliances? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Ezana 19. Who was the first Ethiopian emperor to establish a modern postal system? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Haile Selassie I 20. Which emperor was known for his love of poetry and literature? (a) Tewodros II (b) Menelik II (c) Yohannes IV (d) Emperor Zara Yaqob Answer Key: 1. a 2. b 3. b 4. a 5. b 6. c 7. c 8. b 9. b 10. d 11. b 12. d 13. b 14. a 15. b 16. b 17. c 18. b 19. b 20. d
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12.  The Krebs Cycle takes place in the:      a)  Cytoplasm      b)  Mitochondrial matrix      c)  Intermembrane space of the mitochondria      d)  Golgi apparatus      Answer: b) Mitochondrial matrix 13.  What is the net yield of ATP from one molecule of glucose undergoing glycolysis followed by fermentation?      a)  2 ATP      b)  4 ATP      c)  32 ATP      d)  36 ATP      Answer: a) 2 ATP (Fermentation only yields ATP from glycolysis) 14.  Which of the following steps in cellular respiration directly requires molecular oxygen (O₂)?      a)  Glycolysis      b)  The link reaction      c)  The Krebs cycle      d)  The electron transport chain      Answer: d) The electron transport chain (Oxygen is the final electron acceptor in the ETC) 15.  Uncoupling proteins can disrupt the proton gradient established during chemiosmosis. This would have what effect on ATP synthesis and heat production?      a)  Increased ATP synthesis, increased heat production      b)  Increased ATP synthesis, decreased heat production      c)  Decreased ATP synthesis, increased heat production      d)  Decreased ATP synthesis, decreased heat production      Answer: c) Decreased ATP synthesis, increased heat production (The proton gradient's energy would be dissipated as heat instead of driving ATP synthesis)
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📚Cellular Respiration: Multiple Choice Questions Instructions: Choose the single best answer for each question. 1.  Which of the following is NOT a product of glycolysis, occurring in the cytoplasm of a eukaryotic cell?      a)  Pyruvate       b)  ATP      c)  NADH      d)  FADH₂      Answer: d) FADH₂  (FADH₂ is produced in the Krebs Cycle) 2.  The enzyme phosphofructokinase (PFK) is a key regulatory point in glycolysis. High levels of which molecule would allosterically INHIBIT PFK activity?      a)  AMP      b)  ADP      c)  ATP      d)  Fructose-6-phosphate     Answer: c) ATP  (High ATP levels signal sufficient energy, slowing down glycolysis) 3.  During the link reaction, pyruvate is converted to acetyl-CoA. This process directly results in the:      a)  Reduction of NAD⁺      b)  Production of ATP      c)  Release of CO₂      d)  Both a and c      Answer: d) Both a and c (NAD⁺ is reduced to NADH, and a CO₂ molecule is released) 4.  Which molecule acts as the "final electron acceptor" at the end of the electron transport chain in oxidative phosphorylation?      a)  Water (H₂O)      b)  Oxygen (O₂)      c)  Carbon dioxide (CO₂)      d)  NADH      Answer: b) Oxygen (O₂) (Oxygen's high electronegativity allows it to accept the final electrons, forming water) 5.  The electron transport chain is located in the:      a)  Cytoplasm      b)  Mitochondrial matrix      c)  Inner mitochondrial membrane      d)  Outer mitochondrial membrane      Answer: c) Inner mitochondrial membrane (This location allows for the establishment of a proton gradient) 6.  The proton motive force generated during chemiosmosis is DIRECTLY used for:      a)  Pumping electrons across the membrane      b)  Phosphorylating glucose during glycolysis      c)  Synthesizing ATP by ATP synthase      d)  Reducing NAD⁺ to NADH      Answer: c) Synthesizing ATP by ATP synthase (The flow of protons down their concentration gradient provides energy for ATP synthesis) 7.  Which of the following statements about substrate-level phosphorylation is TRUE?      a)  It occurs only in the electron transport chain.      b)  It involves the direct transfer of a phosphate group from a substrate molecule to ADP.      c)  It requires oxygen as the final electron acceptor.      d)  It is the primary method of ATP production in aerobic respiration.      Answer: b) It involves the direct transfer of a phosphate group from a substrate molecule to ADP. 8.  How many ATP molecules are theoretically produced per glucose molecule during oxidative phosphorylation (including chemiosmosis)?      a)  2      b)  4      c)  32-34      d)  36-38      Answer: c) 32-34 (The exact number can vary depending on the shuttle system used to transport electrons into the mitochondria) 9.  In the absence of oxygen, pyruvate is converted to lactate (lactic acid) in a process called:      a)  Glycogenesis      b)  Gluconeogenesis      c)  Fermentation      d)  β-oxidation      Answer: c) Fermentation (Fermentation allows glycolysis to continue in the absence of oxygen by regenerating NAD⁺) 10. Which enzyme in the Krebs cycle is responsible for catalyzing a substrate-level phosphorylation reaction?      a)  Citrate synthase      b)  Isocitrate dehydrogenase      c)  Succinyl-CoA synthetase      d)  Malate dehydrogenase      Answer: c) Succinyl-CoA synthetase (This enzyme catalyzes the conversion of succinyl-CoA to succinate, producing GTP, which is then converted to ATP) 11.  Which of the following correctly describes the role of NADH and FADH₂ in cellular respiration?      a)  Final electron acceptors in the electron transport chain      b)  Products of ATP hydrolysis      c)  Electron carriers that donate electrons to the electron transport chain      d)  Enzymes that catalyze substrate-level phosphorylation      **Answer: c) Electron carriers that donate electrons to the electron transport chain (They carry electrons extracted from glucose to the ETC)
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📚Cellular Respiration: Multiple Choice Questions Instructions: Choose the single best answer for each question. 1.  Which of the following is NOT a product of glycolysis, occurring in the cytoplasm of a eukaryotic cell?      a)  Pyruvate       b)  ATP      c)  NADH      d)  FADH₂      Answer: d) FADH₂  (FADH₂ is produced in the Krebs Cycle) 2.  The enzyme phosphofructokinase (PFK) is a key regulatory point in glycolysis. High levels of which molecule would allosterically INHIBIT PFK activity?      a)  AMP      b)  ADP      c)  ATP      d)  Fructose-6-phosphate     Answer: c) ATP  (High ATP levels signal sufficient energy, slowing down glycolysis) 3.  During the link reaction, pyruvate is converted to acetyl-CoA. This process directly results in the:      a)  Reduction of NAD⁺      b)  Production of ATP      c)  Release of CO₂      d)  Both a and c      Answer: d) Both a and c (NAD⁺ is reduced to NADH, and a CO₂ molecule is released) 4.  Which molecule acts as the "final electron acceptor" at the end of the electron transport chain in oxidative phosphorylation?      a)  Water (H₂O)      b)  Oxygen (O₂)      c)  Carbon dioxide (CO₂)      d)  NADH      Answer: b) Oxygen (O₂) (Oxygen's high electronegativity allows it to accept the final electrons, forming water) 5.  The electron transport chain is located in the:      a)  Cytoplasm      b)  Mitochondrial matrix      c)  Inner mitochondrial membrane      d)  Outer mitochondrial membrane      Answer: c) Inner mitochondrial membrane (This location allows for the establishment of a proton gradient) 6.  The proton motive force generated during chemiosmosis is DIRECTLY used for:      a)  Pumping electrons across the membrane      b)  Phosphorylating glucose during glycolysis      c)  Synthesizing ATP by ATP synthase      d)  Reducing NAD⁺ to NADH      Answer: c) Synthesizing ATP by ATP synthase (The flow of protons down their concentration gradient provides energy for ATP synthesis) 7.  Which of the following statements about substrate-level phosphorylation is TRUE?      a)  It occurs only in the electron transport chain.      b)  It involves the direct transfer of a phosphate group from a substrate molecule to ADP.      c)  It requires oxygen as the final electron acceptor.      d)  It is the primary method of ATP production in aerobic respiration.      Answer: b) It involves the direct transfer of a phosphate group from a substrate molecule to ADP. 8.  How many ATP molecules are theoretically produced per glucose molecule during oxidative phosphorylation (including chemiosmosis)?      a)  2      b)  4      c)  32-34      d)  36-38      Answer: c) 32-34 (The exact number can vary depending on the shuttle system used to transport electrons into the mitochondria) 9.  In the absence of oxygen, pyruvate is converted to lactate (lactic acid) in a process called:      a)  Glycogenesis      b)  Gluconeogenesis      c)  Fermentation      d)  β-oxidation      Answer: c) Fermentation (Fermentation allows glycolysis to continue in the absence of oxygen by regenerating NAD⁺) 10. Which enzyme in the Krebs cycle is responsible for catalyzing a substrate-level phosphorylation reaction?      a)  Citrate synthase      b)  Isocitrate dehydrogenase      c)  Succinyl-CoA synthetase      d)  Malate dehydrogenase      Answer: c) Succinyl-CoA synthetase (This enzyme catalyzes the conversion of succinyl-CoA to succinate, producing GTP, which is then converted to ATP) 11.  Which of the following correctly describes the role of NADH and FADH₂ in cellular respiration?      a)  Final electron acceptors in the electron transport chain      b)  Products of ATP hydrolysis      c)  Electron carriers that donate electrons to the electron transport chain      d)  Enzymes that catalyze substrate-level phosphorylation      **Answer: c) Electron carriers that donate electrons to the electron transport chain (They carry electrons extracted from glucose to the ETC)
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