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Infectious Disease / Microbiology Updates

Infectious Disease / Microbiology Updates

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All the atest articles, research and news from worlds leading Infectious Disease Journals. Discussion group https://t.me/Professional_Medical_Discussion

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پست‌های کانال
Genomic and Epidemiologic Insights into Ongoing Measles Outbreak, Israel, 2025–2026 https://wwwnc.cdc.gov/eid/article/32/9/26-0625_article

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In the Literature https://academic.oup.com/cid/article/83/1/ii/8740462?rss=1
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State-of-the-Art Review: Infections in Patients With Cerebrospinal Fluid Shunts https://academic.oup.com/cid/article/83/1/1/8740512?rss=1
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[Correspondence] Keep antibiotics habitable: stewardship as climate mitigation https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00109-X/fulltext?rss=yes Friends and family kept asking, “Why infectious diseases?” Although their intent was kind, the subtext was constant: why choose a path that is demanding, less lucrative, and often unseen? I had no slogan in response. I only knew that, since adolescence, I was drawn to infections caused by improbable microorganisms, with protean presentations and diagnostic challenges that leave no room for shortcuts. At first, microorganisms appear as unidentifiable, surreal shapes, until diagnostics and microbiology allow for their identification and characterisation.
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[Correspondence] 25 years of antibiotics: from desperate access to precision safety https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00112-X/fulltext?rss=yes As The Lancet Infectious Diseases approaches its 25-year anniversary, your Editorial1—and its call for stories of success, hope, and inspiration—resonated strongly with our team. In our intensive care unit (ICU), one such story began with an uncomfortable series of questions at the bedside: “Will tigecycline work?”, “Can we keep this patient safe while it works?”, and “Do we have any other options?”
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[Correspondence] The limb-saving power of bedside Gram staining https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00107-6/fulltext?rss=yes As infectious disease physicians, we rarely have a single dramatic procedure that instantaneously changes a patient's trajectory: no emergent catheterisation for acute myocardial infarction, no urgent endoscopy for torrential upper gastrointestinal bleeding. Antibiotics can look deceptively simple—something any competent generalist can prescribe. Our value often appears only later, after the fever has lingered, the tests have failed, and someone finally asks, “What are we missing?” Even then, the resolution can feel quiet rather than cinematic.
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[Correspondence] Tuberculosis treatment with early detection https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00082-4/fulltext?rss=yes Recently, I was working in a densely populated informal settlement in Mumbai, a metropolitan city in India, where tuberculosis was a daily finding in my outpatient department due to the high endemicity. One case, however, stayed with me.
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[Correspondence] Rapid recruitment for a remote long COVID clinical trial https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00070-8/fulltext?rss=yes There have been few long COVID clinical trials relative to the burden of disease,1 and even fewer have been accessible to people with more severe illness.2 As a person who has had moderate-to-severe long COVID (depending on the day) since 2020, I have long advocated for at-home access to clinical trials.3–5
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[Newsdesk] Research in brief https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00366-X/fulltext?rss=yes Reverse-transcription quantitative PCR-based assays for orthoebolaviruses such as Ebola, Sudan, and Bundibugyo viruses are resource intensive and take several hours to provide results, highlighting the need for rapid point-of-care tests. Using previously generated murine monoclonal antibodies specific for orthoebolavirus glycoproteins, researchers in Canada developed a prototype immunochromatographic lateral flow assay to detect glycoproteins from all known orthoebolaviruses. In 10 μL of plasma or whole blood, the test detected Ebola, Sudan, and Bundibugyo virus recombinant glycoproteins at amounts of 62·5 ng or 31·2 ng.
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[Correspondence] Crossing the regulatory and clinical operational valley in antimicrobial resistance: from a start-up's perspective https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00140-4/fulltext?rss=yes The milestone that gave me the greatest satisfaction last year was not a headline-grabbing breakthrough, but the quiet alignment of two parallel worlds: regulatory clearance and operational readiness for BWC0977, a novel dual-targeting inhibitor of DNA gyrase and topoisomerase IV—a class that has seen little innovation in decades.1 BWC0977, a broad-spectrum antibacterial clinical candidate, is currently undergoing a phase 1 trial in Australia.2 It demonstrates broad-spectrum activity against the major WHO-published list of bacterial priority pathogens.
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[Newsdesk] Cold-chain vehicles to support vaccination in Ecuador https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00368-3/fulltext?rss=yes In May, 2026, Ecuador became the first country in Latin America and the Caribbean to procure vaccine-transport vehicles with cold-chain technology. Sanjeet Bagcchi reports.
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[Obituary] Edward Pesanti https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00371-3/fulltext?rss=yes Respected infectious disease expert, physician, and leader in prison health care died on May 27, 2026, aged 81 years.
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[Profile] Krutika Kuppalli—containing infectious disease outbreaks https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00370-1/fulltext?rss=yes In 2014, Krutika Kuppalli served as Medical Director of a large Ebola Treatment Unit (ETU) in Sierra Leone during the West African Ebola virus disease epidemic (2013–16). “It was the most challenging but transformative experience of my life. Even 12 years later, I am learning from it”, says Kuppalli. She is now Associate Professor in the Division of Infectious Diseases and Geographic Medicine at UT Southwestern Medical Center, in Dallas, TX, USA, with a secondary appointment in the Peter O’Donell Jr School of Public Health (OSPH).
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[Profile] Troy Grennan—getting anal cancer the attention it deserves https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00369-5/fulltext?rss=yes Growing up on Canada's East Coast, the young Troy Grennan had a gay neighbour who had moved away to experience 'big city’ life in Toronto. Later when doing his own studies in Toronto, Grennan would volunteer (and later work) at Casey House, a well-known hospice (and now large charity) for those dying from or seriously ill with HIV. He was shocked to find his former neighbour as one of Casey House's patients, and the neighbour sadly died from HIV complications. It was one of many experiences he had at Casey House that left him determined to make a difference for people living with HIV.
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[Correspondence] A defining clinical moment during the COVID-19 pandemic in Nigeria https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00306-3/fulltext?rss=yes Moments that shape careers in infectious diseases are often rooted in uncertainty but clarified by experience. After passing my part one fellowship examination in internal medicine in May 2019, I remained undecided about whether to pursue a career in nephrology or in infectious diseases. This uncertainty was resolved by the emergence of COVID-19 in Nigeria in February 2020, and the rapid establishment of national response structures, including isolation and treatment centres across federal tertiary hospitals.
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[Correspondence] A new era of hope: the impact of long-acting injectables for individuals ageing with childhood HIV https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00303-8/fulltext?rss=yes HIV carries an unwarranted stigma especially in perinatal and prepubescent populations.1 Thanks to the introduction of antiretroviral therapy (ART) during pregnancy, the rate of perinatal HIV transmission has decreased from 20–30% to 0·1–0·5%.2,3 In 2022, nearly 13 000 people in the US were living with perinatal HIV;4 these patients cannot be forgotten. For this perinatal population, daily medication is both beneficial and emotionally challenging. Daily medication can feel burdensome and overwhelming, leading to non-compliance or discontinuation; risking resistance, viraemia, mental anguish, and resentment.
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[Comment] The Bundibugyo virus disease outbreak: a warning signal for risks to health workers https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00364-6/fulltext?rss=yes The ongoing outbreak of Ebola virus disease caused by Bundibugyo virus in DR Congo and Uganda is a reminder that epidemic preparedness remains weak, particularly where it matters most—at the front line. The outbreak was declared a Public Health Emergency of Continental Security and International Concern in May, 2026,1 and at least 1294 confirmed cases, including 362 deaths, have been reported as of June 27, 2026.Beyond the concerning epidemiological trajectory, the disproportionately high incidence of infection among health-care workers is an alarming signal, highlighting persistent vulnerabilities in front-line protection and systems for infection prevention and control.
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[Newsdesk] Trials of medical countermeasures to begin in DR Congo https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00365-8/fulltext?rss=yes Three drugs for Bundibugyo virus treatment and prevention are set to be tested in DR Congo under a previously established protocol for an adaptive platform trial. Esther Nakkazi reports.
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Surveillance of Ticks and Tickborne Borrelia, Ehrlichia, and Rickettsia spp., Texas, USA, 2014–2021 https://wwwnc.cdc.gov/eid/article/32/8/25-1104_article
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Human Lactococcus garvieae Bloodstream Infection Complicated by Spondylodiscitis, Germany https://wwwnc.cdc.gov/eid/article/32/8/26-0334_article
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