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شرح مادة الصيدلة السريرية clinical pharmacology 🧑🏻⚕️ معرف التلي: mohammedsalim10 Instagram: _a1mh
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Regarding treatment of breast cancer. Concomitant or sequential administration of a taxane with an anthracycline-based regimen is mostly standard of care in breast cancer in:
a- Node-positive breast cancer patients with HER2- positive tumors
b- Node-negative breast cancer patients
c- Primary or early-stage breast cancer
d- First line therapy in postmenopausal women with positive ER
e- First line therapy in premenopausal women with positive PR
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Safa is a 33 years old non pregnant woman with metastatic breast cancer that overexpress HER2.
The preferred targeted therapy is
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Manar is a 34 years old non pregnant woman with early breast cancer (stage 0). The
appropriate primary treatment for Manar is
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A 68-year-old woman with history of stage III estrogen receptor (ER)- positive, HER2- negative breast cancer develops metastatic disease involving the bones while on adjuvant exemestane therapy. Her only symptoms are low back pain and right hip pain, corresponding to sites of bony metastases.
Which of the following would be optimal as first-line systemic therapy for metastatic disease?
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Prognostic factors in breast cancer. The HER2 overexpression in breast cancer is very important because
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Drug used to prevent Breast cancer. Which drug increased incidence of endometrial cancer
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Regarding breast cancer management, the adjuvant hormonal therapy of choice for premenopausal women and those in early stage breast cancer which has both estrogenic and antiestrogenic properties is
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Regarding breast cancer. Which of the following cases is at high risk of developing breast cancer?
a- A 25 years-old married female with a history of normal birth of two children.
b- A 59 year-old female who received hormonal therapy because of vasomotor symptoms.
c- A 68 years-old male with BMI 31kg/m2
d- A 39 year-old female with thyroidectomy two years ago.
e- A 41 year-old female with longterm history of dysmenorrhea successfully treated with NSAIDS.
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Chemotherapy for breast cancer is chosen based on the following EXCEPT:
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For the evaluation of the therapeutic outcomes in a patient treated for breast cancer, which of the following is the therapeutic endpoint in the treatment of metastatic breast
cancer?
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36 years old woman with a left breast mass, an excisional biopsy revealed malignant changes, and as a part of her treatment for the cancer, adjuvant endocrine therapy has been prescribed. Which of the following drug can be used as an adjuvant endocrine therapy:
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77-47-year-old woman with a new diagnosis of infiltrating intraductal adenocarcinoma involving the left breast with no regional lymph node involvement, HER2 is negative.
Stage: IIB (T3, NO, MO).
Which of the following item is the most appropriate with this case?
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A 65yr old female patient with stage 1, hormone receptor negative - breast carcinoma
The best management is
a- fluorouracil, doxorubicin, cyclophosphamide without surgical removal
b- fluorouracil, doxorubicin, cyclophosphamide before surgical removal
c- fluorouracil, doxorubicin, cyclophosphamide after surgical removal and radiation
d- only surgical removal and radiation
e- fluorouracil, doxorubicin, cyclophosphamide after radiation
