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The most sensitive investigation for acute infarct (ischemic stroke) is diffusion-weighted MRI (DWI/DW-MRI), especially when a CT scan might appear normal
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Retrograde urethrogram (RGU) is the investigation of choice for urethral strictures and urethral trauma. It specifically visualizes the anterior urethra (bulbar and penile urethra)
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• In cases of aortic dissection, the investigation of choice for a stable patient is CT angiography, while for an unstable patient, transesophageal echocardiography (TEE) is preferred
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• For diagnosing renal tuberculosis (TB), the investigation of choice is a contrast CT procedure known as CT urography.
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Micturating cystourethrography (MCU) is the investigation of choice for both vesicoureteral reflux and posterior urethral wall issues
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For evaluating the integrity of cardiac pacemakers or implantable cardioverter-defibrillator (ICD) devices, the chest radiograph is the preferred investigation
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TB Meningitis: Characterized by a triad of basal exudates, hydrocephalus, and infarcts
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Multiple Sclerosis (MS): On FLAIR MRI, it shows periventricular white matter hyperintensities perpendicular to the ventricle, known as "Dawson fingers". It also shows "horseshoe" or "open ring" enhancemen
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Golden Point-Subarachnoid Hemorrhage (SAH): Characterized by hyperdense sulci and blood collection in the Sylvian fissure, interhemispheric area, and basal cisterns, often described as a "star of death" appearance. The most common cause of spontaneous SAH is the rupture of berry aneurysms, often presenting with a "thunderclap headache". Non-contrast CT is the investigation of choice for acute SAH
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Hallervorden-Spatz Disease (PANK): Eye of Tiger appearance (iron deposition in globus pallidus)
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Neurogenic Bladder: Christmas Tree/Pine Tree appearance.
Posterior Urethral Valve (PUV): Keyhole appearance on antenatal scan (exclusively male child)
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Ga-68 DOTATATE PET for diagnosis and Lu-177 DOTATATE for treatment of neuroendocrine tumors
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