Elmicrobiologist 🔬

Some antibiotics have low or unreliable urinary exposure, which are mainly eliminated by other routes, or are not clinically recommended for routine UTI treatment. ❌ #Tigecycline : Low urinary exposure; only about 22% is excreted unchanged in urine. ❌ #Minocycline & #Doxycycline : Relatively low urinary recovery or excreted changed in Urine. ❌ #Macrolides ( #Erythromycin – #Clarithromycin – #Azithromycin) : They are not routine antibiotics for typical bacterial UTI as it is excreted via hepatobiliary route only. ❌ #Clindamycin : same as Macrolides. ❌ #Moxifloxacin : unlike other Fluoroquinolones, Moxifloxacin is bile excreted. ❌ Oral #Vancomycin : Very poorly systemically absorbed, so it cannot provide reliable urinary concentrations Nor treating systemic infections via oral route. #Elmicrobiologist Dr. Ahmed Mostafa