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312 . explanation Correct answer -D i.e.,BRCA2 mutation is associated with increased risk. The average age of men diagnosed with breast cancer is 68 years (old age). Breast cancers in male have estrogen receptors and high estrogen level is a risk factor for breast carcinoma in males. Men who inherit abnormal BRCA-1 and BRCA-2 genes have an increased risk for male breast cancer. Most breast cancers in men are ductal carcinomas. Join @SURGERYhubs

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311.explanation Correct Answer - C Answer- C. Little toe Ainhum is bilateral painful constriction at the base of 5th toe (little toe). This leads to bilateral auto amputation of little toes. Join @SURGERYhubs

310.explanation Correct Answer - A Answer- A. 1.0 Ankle - brachial pressure index (ABPI) is the ratio of BP in ankle to BP in arm (upper limb). Normal ABPI is around 1 (0.9 - 1.2). Join @SURGERYhubs

309.explanation Correct Answer - A Answer- A. < 0.3 *Lower ABPI is an indication of peripheral vascular disease of lower limb. *Critical ischemia (restpain or tissue necrosis) most commonly is associated with an ABI < 0.4. Join @SURGERYhubs

308.explanation Correct Answer - A Answer- A. Splenic trauma In splenic rupture the pain may be referred to the tip of the left shoulder. This is known as Kehr's sign. It occurs due to irritation of the undersurface of the diaphragm with blood and the pain is referred to the shoulder through the affected fibres of the phrenic nerve (C4 and C5). Join @SURGERYhubs