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| Mensajes | Vistas | Acciones | Ver dinámicas |
01 Media files | 83 | 7 | Loading... |
02 Media files | 82 | 4 | Loading... |
03 Media files | 87 | 2 | Loading... |
04 Media files | 79 | 7 | Loading... |
05 Media files | 187 | 0 | Loading... |
06 🙂↔️🙂↔️ | 240 | 0 | Loading... |
07 https://www.instagram.com/reel/C5_Z4y7sg9Z/?igsh=N3Aya3dvNGE1azJ0 | 240 | 0 | Loading... |
08 Media files | 255 | 29 | Loading... |
09 Media files | 56 | 4 | Loading... |
10 Media files | 268 | 47 | Loading... |
11 Media files | 1 | 0 | Loading... |
12 هسه لو كل واحد يجيبلي هدية يصير عندي 438 هدية 🙂↔️ | 14 | 0 | Loading... |
13 أعيش وارسم البسمة ع وجوهكم 🙂↔️♥️ | 261 | 0 | Loading... |
14 احد عندة فويس الملزمة الرابعه ؟ | 194 | 0 | Loading... |
15 Dosage form lec.5
د. گيلاني | 16 | 0 | Loading... |
16 Dosage form - lec. 4 pharmaceutical and formulation consideration part
د. گيلاني | 1 | 0 | Loading... |
17 #Biotechnology | 204 | 18 | Loading... |
18 Media files | 51 | 0 | Loading... |
19 طلعت كورس اول خامس | 47 | 0 | Loading... |
20 اسئلة العضوية مرحلة رابعة 👆🏻 | 94 | 5 | Loading... |
21 Passive الي م بيه homing devices
Active الي بيه homing device | 74 | 3 | Loading... |
22 هذا بالآسي اول واحد | 62 | 3 | Loading... |
23 هذا بالأسي الأخير
يمكن * | 70 | 3 | Loading... |
24 Media files | 75 | 3 | Loading... |
25 عدد ٣ مشاكل حليناها بال pro drug | 68 | 3 | Loading... |
26 1-Aspirin activation in acidic media of stomach
2- Bipartite prodrug have spacer F
وجاب نقطة ثانية انو
Tripartite have a spacer T
3- co drug is type of prodrug
4- soft / hard is type of prodrug
5- succinate and phosphate increase water solubility
6- phase 2 is transformation او bio precursor
7- The term “pro-drug” or “pro-agent”with a dash was coined
ما اذكر شنو اسم العالم بس جان F
8- prodrug is rare phenomena according to albert
9- antibody passive or active targeting
10- soft drug / hard drug
جان ثنينهم جوابهم B بس ما اذكر النقاط mcq
12- prodrug mcq
نقطة D العالم Adrien albert
13 - PEG is synthetic polymer
14- IUPAC considered both Prodrug and Drug Latentiation as synonyms in
1998
15- Dextran methylprednisolone succinate in liver and spleen ( mcq)
Definitions prodrug /codrug
Ideal characteristics of prodrug
What is barrier to form prodrug اعتقد هيج جان
Structure
1- aspirin
2- Hetacillin
3- Estramustine
4-Nabumetone (Relafen)
وجاب عليها T/F هم انو تختزل
بس ذني الي اذكرهم🤍
#اسئله المد_عضويه | 91 | 3 | Loading... |
27 Q1/ Choose the correct answer (answer only 10) (30 marks)
1. Promoiety succinic acid is added to Chloramphenicol is to :
a. Increase activity.
b. Decrease toxicity.
c. Increase polarity.
d. Increase lipophilicity.
2. NSAID Sulindac is belong to :
a. Carrier-linked prodrug
b. Mutual prodrug
c. Not prodrug
d. Bioprecurssor prodrug
3. Prodrug agent that contain carboxylic acid side chain and promoiety alcohol side chain is convert to:
a. Ketone bond
b. Aldehyde bond
c. Acetic anhydride bond
d. Ester bond
4. Phosphorylation of Clindamycin is to form prodrug for:
a. Increase water solubility
b. Increase lipid solubility
c. Decrease toxicity
d. Decrease stability
5. Methenamine release in urine as:
a. Ester
b. Aldehyde
c. Ketone
d. Carboxylic acid
6. Enzyme that act on Sulfasalazine to form Sulfapyridine and aminosalycilic acid :
a. Amino reductase
b. Sulfa-hydrolase
c. Azo reductase
d. Esterase
7. PepT1 transporter is important in drug absorption due to:
a. Improve good permeability
b. Improve good bioavailability
c. Improve good penetration to brain
d. Improve good excretion
Mid exam for 5th stage
8. Is the main enzyme that act in reductive activation of bioprecursor prodrug:
a. Ester reductase
b. cytochrome P-450 reductase
c. cytochrome P-450A1B3 reductase
d. cytochrome P-450A1B7 reductase
9. Is the drug used for Zollinger–Ellison syndrome:
a. Idoxuridine
b. Dipivefrine
c. Omeprazole
d. Oleanoic acid
10. In Cancer Cells Targeting sometimes targeting to :
a. Glucosidase
b. β- glucuronidase
c. Glucose reductase
d. Galactose esterase
11. L-dopa is converted to dopamine by:
a. Dopa transferase
b. Deaminase
c. Decarboxylase
d. Dehydrogenase
Q2/ discuss briefly? (answer only two) (20 marks)
A. Why Pivalic acid promoiety is linked to epinephrine and formation of Dipivefrine?
B. Why alkyl carbamates is linked to Terbutaline as promoiety?
C. Bacampicillin formation as prodrug? | 63 | 3 | Loading... |
28 بايو بركيسير نقل الدواء بدون ناقل
من خلال الإنزيمات ( phase 1,phase 2) | 59 | 3 | Loading... |
29 Media files | 69 | 3 | Loading... |
30 Mechanism of targeting :
Passive
Active | 60 | 3 | Loading... |
31 مهم اسمه | 64 | 3 | Loading... |
32 إذا جاب فد مركب وعلى السهم ال GSH
نروح ع اي sh بالمركب ونكسرها | 65 | 3 | Loading... |
33 برو دراك
وti
By all
Deactivation
هاي مال liver جان ترو فولس او اختيارات ؟
تعريف البرو دراگ
Liver and spleen
Hard drug not metabolism by all]
Soft drug Deactivation
Felix
ADEM
By active and passive
#اسئله المد عضويه | 91 | 5 | Loading... |
Repost from Pharmacy World
اسئلة_تدريب_صيدلة_مستنصرية_للعام_السابق.pdf6.03 KB
اسئلة تدريب جامعة بغداد(1).pdf2.32 MB
جامعة ذي قار.pdf1.17 KB