pharmacy all semester notes and study material previous year qus

Electrocardiogram ✅

🧠 Drug-Induced Syndromes ➡️ 🩺💊 1. Amiodarone → Blue Man Syndrome 👉Mechanism: Skin discoloration due to dermal lipofuscin deposits after long-term use. 👉Clue: “Amiodablue” = Amiodarone turns you blue (phototoxicity-related). 🩺💊2. Aspirin → Reye's Syndrome 👉 Mechanism: Aspirin use in children with viral illness → mitochondrial dysfunction → acute encephalopathy + hepatic failure. 👉Mnemonic: “Aspirin in kids? Think ‘Reye-sy’ reaction!” 🩺💊3. Chloramphenicol → Gray Baby Syndrome 👉Mechanism: Immature UDP-glucuronyl transferase in neonates → drug accumulation → hypotension, cyanosis, gray skin. 👉Clue: Chlor-amphanicol? More like Chloro-GRAY-nicol. 🩺💊4. Clindamycin → Stevens-Johnson Syndrome (SJS) 👉Mechanism: Severe immune-mediated hypersensitivity (Type IV). 👉Mnemonic: Clinda can "clean da" skin off — literally. 🩺💊5. Corticosteroids → Cushing’s Syndrome 👉Mechanism: Excess exogenous corticosteroids → HPA axis suppression → iatrogenic Cushingoid features (moon face, central obesity). 👉Mnemonic: Too many "cortico-snacks" = Cushing’s pack. 🩺💊 6. Phenytoin → Purple Glove Syndrome 👉Mechanism: IV phenytoin extravasation → soft tissue necrosis and purple discoloration of limbs. 👉Clue: Purple gloves? Handle phenytoin with care. 🩺💊7. Vancomycin → Red Man Syndrome 👉 Mechanism: Non-IgE-mediated histamine release due to rapid infusion → flushing, rash, hypotension. 👉Mnemonic: “Van-go too fast? Red flow’s the blast.” 🩺💊8. Warfarin → Purple Toe Syndrome 👉Mechanism: Cholesterol microembolization → painful purple discoloration of toes. 👉Clue: Warfarin wars → tiny clots, purple spots. 🧪 Exam Tip: Associate the drug + color to remember: 🔵 Amiodarone – Blue 🔴 Vancomycin – Red 🟣 Phenytoin & Warfarin – Purple ⚫ Chloramphenicol – Gray