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As for the brain center for the step-siblings shit, it is yet to be elucidated

In humans it's even more fucked up: A lesion in the amygdala can make the patient hypersexual, pervert, and basically sexually uninhibited. Apparently we're one of those very few species who have fear, aggression, and sex all mixed up in one place. For more reference, check the meaning of BDSM (but don't check BDSM).

The amygdala is one of those fucked up (hence, interesting) structures. Researchers at first thought that it's the center responsible for aggression, because whenever they provoked it, the lab rat would go berserk. We later found out that it's actually responsible for fear & negative emotions. And aggression is basically a response to fear.

Behavioral evolution 101 What is common in those 4 events? Having your period Taking anabolic steroids Having a brain tumour Eating a lot of junk food You see, a smart fellow would say " Hormones " which is correct But a brilliant one would say that they all were used to reduce the sentence in a court of law. A woman blaming her period for the emotional instability A diebtic patient blaming junk food for not controlling his emotions Heavy weight lifter being hostile due to taking steroids And of course the guy with the brain tumor in the amygdala causing aggressive behavior It shows the connection between the body and the brain What happens to the body effects the brain and vice versa

جاوبوه ولكم الأجر والثواب

- El Camino, a Breaking Bad movie

These descriptions of human misery, in addition to their beauty, they are like acts of empathy... Hugs from a distant place and time. They tell us that we are not alone in our misery and suffering.

مِسْكِينٌ اِبْنُ آدَمَ مَكْتُومُ اَلْأَجَلِ مَكْنُونُ اَلْعِلَلِ مَحْفُوظُ اَلْعَمَلِ تُؤْلِمُهُ اَلْبَقَّةُ وَ تَقْتُلُهُ اَلشَّرْقَةُ وَ تُنْتِنُهُ اَلْعَرْقَةُ - علي بن أبي طالب (ع)

جزء جبير من الرعب اللي يسببه السفلس هو أنّه حرفيًا "ياكل" اللحم والغضاريف والعظام. يعني هواي مرضى تشوف عدهم قروح تمتد من الجلد وصولًا للعظم، كأنما أكو أحد حافرها عمدًا.

يكلك هلكد ما السفلس جان خطير ومخوّف الناس بأيام قبل، جانوا يجربون وياه علاجات خطيرة تكاد تكون بنفس سوء المرض. مثلًا جانوا ينطون للمرضى زئبق (ويسببون الهم تسمم مزمن بالزئبق) حتى يقتلون بكتيريا السفلس ويعالجوه. أو ببداية القرن الـ 20 جانوا يُصيبون المرضى عمدًا بالملاريا لأنها تسببلهم حمى عالية بما فيه الكفاية لطبخ بكتيريا السفلس بداخل جسم المريض وبالنتيجة علاجه.

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The story of Syphilis: Columbus may have brought one killer disease back from the Americas: syphilis. This broke out in 1493-4 during a war between Spain and France being waged in Italy. When Naples fell to the French, the conquerors indulged in the usual orgy of rape and pillage, and the troops and their camp-followers then scattered throughout Europe. Soon, a terrible venereal epidemic was raging. It began with genital sores, progressing to a general rash, to ulceration, and to revolting abscesses eating into bones and destroying the nose, lips and genitals, and often proving fatal. Initially, it was called the 'disease of Naples', but rapidly became the 'French Pox' and other terms accusing this or that nation: the Spanish disease in Holland, the Polish disease in Russia, the Russian disease in Siberia, the Christian disease in Turkey and the Portuguese disease in India and Japan. For their part, the Portuguese called it the Castilian disease, and a couple of centuries later Captain Cook (1728-79), exploring the Pacific, said that the Tahitians 'call the venereal disease Apano Britannia - the British disease' (he thought they'd caught it from the French). - The Greatest Benefit To Mankind

The wholesale destruction of indigenous New World populations continued for over three hundred years; twenty million slaves had to be shipped to America to fill the vacuum, causing cruelty and suffering on a scale not matched until the regimes of Hitler and Stalin.

Between 1518 and 1531, perhaps one third of the total native American population died of smallpox, while the Spanish hardly suffered. With allies like microbes, the Europeans did not require many soldiers or much military acumen. Guns and germs enabled small European bands to conquer half a continent in what might be called, to echo Gibbon, another victory of barbarism over civilization.