𝐙𝐀𝐆 𝐃𝐨𝐜𝐭𝐨𝐫𝐬 57 || Scheme

Data that should be included on sample: لازم تحط البيانات دي على العينة علشان ال NAS TSTPhAD ناس تستفاد Name Age Sex Time and Source of sample Test requested Physician referring Antimicrobial taken Diagnosis Suspected Criteria of sample rejection: هنرفض العينة بسبب مشكلتين في ال sample Unlabeled or mislabeled Contaminated مشكلتين في ال container Leaky Not suitable for sample type و مشكلتين delay Transport Processing

Eye Graphs Miosis Present lid twitch = present Nicotinic Mydrasis L+L = P+P Light reflex Lost --> Passive mydrasis by Parasympathetolytic Mydrasis + Lost Corneal reflex --> Cocaine No pupil effect + Lost Corneal reflex --> Surface anesthesia other than cocaine (Tetracaine) No pupil effect + Corneal reflex intact --> infeltrative anesthesia (Procaine)

فروقات مهمة pharma 🟡كل ال routes of administration ينفع نقول في ال disadvantage بتاعها irritation ما عدا IV لأنه لل irritant drugs 🟡كل ال routes of administration. ماعدا ال oral ينفع نقول في ال advantage بتاعها Bypass first pass metabolism Not affected by GIT PH and enzyme 🟠الدواء لو non-oily و soluble --> ناخده IV 🟠الدواء لو oily و insoluble--> ناخده IM 🟢ال spinhaler--> بناخد بيه الدواء ال powder 🟢ال MDI --> بناخد بيه الدواء ال Aerosol 🔵ال ointment--> ناخده لل dry lesion 🔵ال cream --> ناخده لل semi-wet lession 🔵ال lotion--> ناخده لل wet lesion

🚨Take Care ■ Chemotherapy - Treatment of MRSA --> Vancomycin & Rifampicin - Treatment of Gonnorhea --> 1st line cephtriaxone, second line oflocxacine - Treatment of gonnococcal uretheritis --> cotrimexathone - Red man Syndrome--> Vancomycin S.E - Grey Baby Syndrome--> Chloramphenicol S.E ■ ANS - Alpha blocker reverse the hypertensive action of Adrenaline - Atropine reverse the hypotensive action of Ach - Beta Blockers cause early VC then VD - Atropine cause paradoxical Bradycardia at first then tachycardia - Non selective Alpha blocker like phenoxbenzamine --> hypotension and reflex tachycardia - Selective Alpha 1 blocker like Prazosin --> hypotension and NO tachycardia - Mary's reflex cause Bradycardia with Norepinephrine - Bezold Jarish reflex cause Bradycardia with serotonin ■ Autacoids - Keep patency of ductus arteriosus --> Eicosanoid --> alprostadil - Treatment of patent ductus arteriosus -->  Eicosanoid Inhibition--> indomethacine

💥 ttt of Antiparkinsonism - Amantadine & rimantadine - Bromocryptine - Atropine & benotropine & benzohexol - Diphenhydramine 💥 Avoid in parkinson -pilocarpine -alpha methyle tyrosine 💥 cause crystalluria -sulphonamide -Acyclovir -alpha methyle tyrosine

➡️Amphetamine Derivatives • Methamphetamine: - زي الamphetamine بس زيادة على المخ (more CNS action) • Methylphenidate: -  فيه DA يبقى لل ADHD • Modafinil: - فيه DA يبقى لل ADHD بردو - فيه f يبقا شغال على five HT receptor بتاع ال serotonin - و moda يبقى شغال على receptors ال mood زي بتاعة ال serotonin و ال glutamate و alpha - مسؤول عن النوم (narcolepsy) • Phenmetrazine & Diphenmetrazine: - فيه كلمة metr يبقى يفكرنا إن كرشه متر قدامه (obesity) • Fenfluramine & Dexfenfluramine: - فيه f يبقا شغال على five HT receptor ف بيسرع ضربات القلب (Arrhythmia) ➡️Neostigmine substitutes •Demecarium: شغال على ال eye لل glucoma •Benzpyrinum: لل paralytic ileus •Edrophonium: قدر يفرق بين ال myasthenia و ال cholinergic crisis •Ambenonium & pyridostigmine: أحسن و stigmine إنه أحسن من Neostigmine ➡️Atropine substitutes • Antisecretory Antispasmodic drugs: سيلين و ياسين و زين - Propanthelene --> increase GIT motility - Hyoscine N-butyl bromide --> relax GIT spasms - Pirenzepine & telenzepine --> peptic ulcer • Antiasthmatic: Ipratropium & Tiotropium --> by inhalation • Antiparkinsonism (Brain): Benztropine & Benzhexol و بعدين معانا حاجتين: ١) حاجة بتضيق • Urinary Incontinence: Oxbutynin ,empepronium, tolterodine ٢) حاجة بتوسع • Eye mydratics: Homatropine, tropicamide, cyclopentolate

السلام عليكم ورحمة الله وبركاته حاليا كل المواد بقا متاح ليها سكيمات و mnemonics لل written إن شاء الله تساعدكم في الحفظ كلهم متجمعين الماسدج دي لتفاصيل أكثر و تجميعات لل MCQ دي الماسدج الأساسية

📝 Written

Patho 🔬

•Tissue repair • Inflammation • Tissue deposition • Circulation • Neoplasia Part 1 — Part 2

Micro 🦠

- ريتن المايكرو (grade A)

Para 🪱

- ريتن البارا (grade A)

Pharma 💊

- أسئلة ريتن grade A لشباتر General Pharmacology - أسئلة ريتن grade A لشباتر Chemotherapy+PI - سكيمة ثابتة لريتن adverse effects of chemotherapy - تجميعة uses الأدوية - تجميعة A.E الأدوية - uses of Ephedrine - uses of Atropine  - uses of antihistamines - uses of Serotonin - uses of Eicosanoids

Periphral vascular disease 1 Contraindications -beta blocker -ephidrine -ergot alkaloids 2 uses -eicosanoids -ketanserin

Prophylaxis of migrain 1 cyproheptadine 2 pizotifen 3 clonidine 4 betablocker ttt of migraine 1 ergotamine 2 sumatriptane

Alzheimer's drugs رفدوا جلال علشان نسي Rivastigmine Physostigmine Donepezil Galantamine

Failure of bone union ?

Complications of abscess + Complications of wound healing

Irreversible binding to site of action Aminoglycoside Irreversible binding to 30s subunit Organophosphorus Irreversible binding to esteritic site of choline esterase Phenoxybenzamine Irreversible binding to alpha receptors

وفي الامسكيو البحر فيه ماء والماء فيه hydrogen فنختار الدوايين اللي فيهم hydra في النص Diphenhydramine Dimenhydranate