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Repost from Quiz-UOBCOM95
Which one of the following cells would be most effective defence against Adult in Schistosoma in the vesical plexuses?
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Repost from Quiz-UOBCOM95
Lymphocytes expressing both the CD4 and CD25 markers on their surfaces function as:
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Repost from Quiz-UOBCOM95
A 42-year-man complains of several months of weight loss, night sweats, mild sputumproduction, and the spitting up of blood. You run a PPD (tuberculin skin test) and theresults are positive. 29 amounts of IL-2, IFN-Y, andTNF. The immune cell responsible for Patients with tuberculus granulomas that have elevated this pattern of cytokine production is the :
A. Cytotoxic T lymphocyte
B. Epithelioid cell
C. Lack cell
D. TH1 cell
E. TH2 cell
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Repost from Quiz-UOBCOM95
When you Vaccinated with Sinopharm Covid-19 vaccine, the type of immunity is:
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Repost from Quiz-UOBCOM95
Patients with tuberculus granulomas that have elevated amounts of IL-2, IFN gamma, and TNF. The immune cell responsible for this pattern of cytokine production is the
Select one:
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👑 A lymphocyte population is isolated that:
🔹Does not require APCs
🔹Has no immunologic memory
🔹Is CD3 negative
🔹Kills through Fc receptor interaction
🔹Which receptor is MOST important for its cytotoxic mechanism?
🔹A) CD28
🔹B) CD16
🔹C) CD40
🔹D) CD21
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👑 A patient develops overwhelming inflammation and hypotension after exposure to a bacterial exotoxin that activated a large population of T helper cells without antigen processing. Which cytokine is MOST directly responsible for the systemic toxic manifestations?
🔹A) IL-4
🔹B) IL-5
🔹C) TNF
🔹D) TGF-β
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⭐️ T cells = 60–80% of total lymphocytes
⭐️ B cells = 15–35% of total lymphocytes
⭐️
CD4 → T helper cell (Th)
CD8 → Cytotoxic T cell (Tc)
CD25 → Treg marker
CD3 → all T cells
CD56 → NK cell marker
CD16 → Fc receptor on NK cell (ADCC)
CD19, CD20, CD21 → B cell markers
CD28 → T-cell co-stimulation receptor
⭐️
Th1 cytokines = IL-2, IL-3, TNF, IFN-γ.
Th2 cytokines = IL-4, IL-5, IL-6, IL-10, IL-13.
Treg/Th3 cytokines = TGF-β and IL-10.
IFN-γ activates macrophages and NK cells.
IL-2 is the major T-cell growth factor.
IL-4 is important for IgE class switching.
IL-5 is associated with eosinophils.
IL-10 is anti-inflammatory.
IL-12 activates NK cells.
TNF is heavily involved in toxic shock syndrome.
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CD3 (signal transduction) presents in ALL
T lymphocytes (marker)
People with CD3 deficiency are immunocompromised & vaccines aren’t effective with them (no signal is transduced to activate)
