أمراض الطب

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أسئلة الأمراض النظري / المادة Kidney and prostate

Q4/ Regarding papillary renal cell carcinoma: V A. Associated with VHLgene mutation B.Never bilateraf occurrenice C.Most.common >80% of renal cell tumors D. Associated with tuberous sclerosis E.3 cm is the size cut-off separating it from renal papillary adenoma Q5/VHI. gene mutation is known to be associated with this Tumor A. Angiomyeloma B.Papillary renal cell carcinoma C.Oncocytoma D.Clear renal cell carcinoma E. Collecting duct tumor Q3/7 years old boy presented to the emergency department with abdominal pain and vomiting,the child reported knee pain atso,examination reveated BP 140/90, mild leg edema, purpuric skin rash on buttocks and upper thighs , what is the most probable diagnosis? A. IgA nephropathy (berger's disease) B. Henoch-Scho"nlein Purpura C. Membranous nephropathy D.Rapidily progressive GN E. focal segmental GN Q1/30 years old man noticed decreased urination in the past 2 days the patient reported no dysuria or hesitancy,but he had a single episode of coughing up bioody mucous the general examination revealed that BP.was180/ 100,mild legedema, blood urea andserum creatinine are markedly elevated,renal blopsywastakenandrevealed-crescent.formationin most of glomeruli with no immune reaction on immunofluorescent examination,what is the diagnosis? . A. good pasure syndrome B. wegners granulomatosis C. IgA neptiropathy D. Microscopic Polyangitis E. Focal segmental glomerulonephritis Q2/ A 3 vear-old girt has become Increasingly lethargic over the past 2 weeks. On examination she has pufliness around the eyes. Her temperature is 36.9" C, and blood pressure is 100/60 mm Hg.Laboratory findings show serum creatinine, 0.7 mg/dL; blood urea nitrogen, 12.mg/dl;and cholesterol, 217 mg/dl Urinalysis 44 protelnuria. The 24-hour urine protein level is 3.8 g. The chlld's condition improves after glucocorticold therapy. Which of the following findings by electron microscopy is most likely to characterize this disease A. Areas of thickened and thinned basement membrane B. Effacement of podocyte foot processes C . Iincreased mesangial matrix D. Reduplication of glomerular basement membrane E. Subepithelial electron-dense humps Q10/benign prostatic hyperplasiə A. usually involve the peripheral zone of prostate B . it is precursor lesion for prostatic CA C. basal layer is lost microscopically D. micrpscopically there are multipie nodules that consist of proliferating gands and fibromuscular stroma E. PSA is normal Q9/Prostatie edenocarcinoma: A. diesemination to bone, occur most often in the form of osteoclastic (radiolucent ) metastases B. neaplastic glands lined by single layer of epithelium C. grade have no role in prognosts D . PSA in organ and cancer specific marker for prostatic carcinoma E. Gleason score grading system depend primarily on cytological leatures of the tumer Q8/ this type of GN is autoimmune caused by autoantibodies) in about 85%.of patients- A. Pest infectioin ON B. Focal segmental GN C. Minimal chenge disease D. Rapidly propressive GN E. Membranous nephropathy Q7/ Class III lupus nephritis is characterized by: A. focal, segmental or global endo or extracapillary glomerulonephritis involving <50% of glomeruli B. Mesangial hypercelullularity and/or mesangial expansion by LM C. Diffuse subendothelial deposits can cause wire-loop appearance D. > 90% globally sclerosed glomeruli E. Glomerulinormal by light microscopy (LM), mesangial deposits by immunofluorescence (IF)/ electron microscopy (EM) Q6/45 years old male presented with worsening malaise and bilateral legs swelling over the past 2 years,On examination he has perlorbltal edema.Laboratory findings include serum creatinine and urea nitrogen are mildly elevated .A renal blopsy is performed and on microscopic examination shows globular hyper cellularity,lectron microscope showed subepithelial spike formation.,these histopathological findings are goes with A. Post infectious glomerulonephritis B. Minimal change GN C. Membranous nephropathy D. Lupus nephritis E. Diabetic nephropathy

أسئلة الأمراض بقالي سؤالين شوكت ما يصير الي مجال اكتبهن و ادز كل الأسئلة

مدام قال هيج فهي Good pasture S

إذا بس هاي الكلمة ممكن اشوفها بال Good P Wegners granulomatosis

أفكر ب renal or respiratory cause بهذا العمر وعنده تقيء دموي فهذا غالباً TB ولكن لابد يعطيني حرارة و تعرق وكذا لحتى اقول ممكن TB واستعبد ال renal cause

فممكن تجيب كلمة وحده وما تذكر ال linear وتقول ال differentional diagnosis فنذكر إثنين من هالمسببات

أما بالنسبة لل test حتى افرق فهو Immunofluorescent إذا طلع linear فهو Good pasture وإذا طلع pauci immune لل wegner وإذا طلبت blood test ف أكيد ال ANCA والي هو ANCA-C