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منشورات القناة
بالنسبة للي يسألون عن مصادر المذاكره لقسم الأطفال: ١. ملف د. مهدي المصحح (للاسف فيه كم خطأ مثال سؤال 177 جوابه A + سؤال 204 جوابه B) ٢. MG ٣. توب جيز (اعتمدوا الاجابات الاخيره لان بعض الاسئله يغيرون اجابتهم) AA: ما فتحت ملفات د. صفدر ابدًا AH: فتحتها كبدايه مذاكرتي للاختبار في جولاي ولو رجع فيني الزمن ماذكرت ملف د.صفدر لانه دسم وياخذ وقت طويل الافضل من وجهه نظري مذاكره الاسئله اليوميه بعد ملف مهدي. المراجعه قبل الاختبار: الاسئله الصعبه الي تحددونها من الاسئله اليوميه + MG + المايلستون والفاكسين تبع شهر اختباركم.

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☝🏻كفو والله ❤️‍🔥 أحب الصنف هذا من البشر 🌹🫡
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Pediatric_100%.pdf
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‏السلام عليكم ورحمة الله وبركاته، احنا طالب وطالبة من جامعة الملك فيصل الحمدالله حصلنا على درجة 100 في قسم الأطفال في اختبار نوفمبر. ‏حبينا نسوي ‏ملف نجمع فيها الاسئلة اللى جاتنا ونرسلها لكم. وهذه المبادره بإذن الله راح تستمر لسنوات عديده بحيث كل سنة يمسكون القناة الي جابوا ١٠٠٪؜ بقسم الاطفال. واي شخص جاب ١٠٠٪؜ بقسم الاطفال، اكتب لنا حسابك بالتلقرام بحيث نجمع اكبر عدد ممكن من الاشخاص الي جابوا ١٠٠٪؜ بقسم الاطفال. Telegram: @SMLE_pediatric وبالتوفيق يا رب 🙏
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☝🏻من هنا أول رسالة في قناة البيديا
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☝🏻Beginning of SMLE Notes (Pedia)
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Tanner Stages
Tanner Stages
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#Milestones
#Milestones
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Osgood schlatter disease 🦵 • Traction apophysitis • Age 9-14 yo • Sx: Tender lump over tibial tuberosity • Self-limiting Infantile Colic • In 3-6 months old babies • Dx: crying lasts for >=3 hr/d, >=3 d/week, for >=3 weeks • Mx: behavioral change Sudden Infant Death Syndrome SIDS • RF: prematurity, prone sleeping, smoking, family hx of SIDS • Prevention: - Sleep in supine position - Use pacifier during sleep - Firm mattress, no pillows/blankets/stuffed animals🛏️ - In the first 6 mo: sleeping in the same room w/o bed-sharing - Smoke-free🚭🙅‍♀️ - Avoid overheating - Breastfeeding 🤱 until at least 4 mo - Placing an infant prone while they’re awake Primary protein-energy malnutrition Main types: Marasmus: - Sx: Muscle wasting, loss of subcutaneous fat, no edema - Deficiency: All major nutrients Kwashiorkor: - Sx: Bilateral pitting edema, distended abdomen, hepatomegaly - Deficiency: Protein Infantile Beriberi • Caused by vitamin B1 deficiency • Sx: anorexia, edema, aphonia Scurvy (Vitamin C Deficiency) • Sx: Follicular hyperkeratosis, gingivial hypertrophy, enlarged bluish purple friable gums Common cause of vomiting in infants -> UTIs Maternal phenobarbital consumption causes low vitamin K in fetus -> Prenatal 1 mg vitamin K1
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#Fluid_Management 💦 Indications for IV fluid: 1) Resuscitation 2) Replacement 3) Maintenance 1) Resuscitation (in shock) 10-20 cc/kg over 20-60 min 2) Replacement - Dehydration % x wt (kg) x 10 - Bolus given to moderate-severe dehydration ^Degree of dehydration: Mild: 5% (<2 yo), 3% (>2 yo) Pulse: N BP: N Urine output: Decreased Oral mucosa: Slightly dry Ant fontanelle: N Eyes: N Skin turgor: N CR: N (<2 s) Moderate: 10% (<2 yo), 6% (>2 yo) Pulse: Rapid BP: N to decreased Urine output: Markedly Decreased Oral mucosa: Dry Ant fontanelle: Sunken Eyes: Sunken Skin turgor: Decreased CR: N to increased Severe: 15% (<2 yo), 9% (>2 yo): Pulse: Rapid, weak BP: Decreased in shock Urine output: Anuria Oral mucosa: Parched Ant fontanelle: Markedly Sunken Eyes: Markedly Sunken Skin turgor: tenting CR: Increased 3) Maintenance Holliday-Segar Method: 100:50:20 rule (24 hr) First 10 kg: 100 cc/kg Second 10 kg: 50 cc/kg Remaining kilos: 20 cc/kg
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#Toxicology 💊 Toxicity agents & their antidotes: Paracetamol: N-acetylcystine TCA: Sodium bicarbonate Aspirin: Sodium bicarbonate Narcotics: Naloxone Iron: Deferoxanine Lead: D-penicillamine Copper: D-penicillamine Organophosphates: Atropine Acetaminophen Toxicity Phases Phase 1 • 0.5-24 hours after ingestion • Sx: asymptomatic or report anorexia, nausea or vomiting, and malaise • PE: reveal pallor, diaphoresis, malaise, and fatigue Phase 2 • 18-72 h after ingestion • Sx: right upper quadrant abdominal pain, anorexia, nausea, and vomiting • PE: Right upper quadrant tenderness, Tachycardia and hypotension Phase 3: Hepatic phase • 72-96 h after ingestion • Sx: continued nausea and vomiting, abdominal pain, and a tender hepatic edge, jaundice, coagulopathy, hypoglycemia, and hepatic encephalopathy • Acute kidney injury Phase 4: Recovery phase • 4 d to 3 wk after ingestion • Patients who survive critical illness in phase 3 have complete resolution of symptoms
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#Rheumatology 🦴 Transient Synovitis vs Septic Arthritis • Sx: Transient: Well-appearing, Afebrile Septic: ill-appearing, febrile🤒, non-wt bearing • Dx: Septic: synovial fluid WBCs >=50,000 • Tx Transient: conservative Septic: drainage & Abx Juvenile Idiopathic Arthritis JIA • Dx: Persistent arthritis lasting for >6 w • Females > Males • All 4 types have negative RF, except in Seropositive Polyarticular JIA • Uveitis screening:👁️ +ANA: every 3-6 mo (in <7 yo), every 6 mo (in >=7 yo) -ANA: every 6 mo Systemic JRA: every 12 mo • Types: Oligoarticular JIA (Most common) • Arthritis: <=4 joints, asymmetrical, large joints • Extra-articular sx: Anterior uveitis👁️ • Tx: NSAIDs💊 Seronegative polyarticular JIA • Arthritis: >=5 joints • Tx: MTX and NSAIDs💊 Seropostive polyarticular JIA • Arthritis: >=5 joints, symmetrical • Extra-articular sx: Rheumatoid nodules • Dx: RF positive • Tx: MTX and NSAIDs💊 Systemic JIA (Still’s disease) • Arthritis: >=1 joint AND intermittent fever🤒 AND extra-articular sx • Extra-articular sx: - Transient migratory salmon-pink rash🍣 - Generalized lymphadenopathy • Dx: Anemia, leukocytosis, thrombocytosis Henoch-Schonlein Purpura HSP • Most common vasculitis in children👧 • Often has Hx of URTI 1-3 w before sx onset • Sx: IgA deposits in small vessels of skin, joints, GI, and kidney - Palpable purpura (buttocks, LL) - Arthritis/arthralgia - Abdominal pain, Intussusception - Renal disease • Dx: Normal Plt ⬆️Cr, Hematuria🩸 • Tx - Hydration & NSAIDs - Severe: Systemic CS Kawasaki Disease • 90% age <5 • Diagnostic criteria: Fever >=5 d + >=4 of the following: - Conjunctivitis (bilateral👁️👁️, nonexudative) - Mucositis: fissured lips/pharynx, strawberry tongue👅🍓 - Rash (erythematous generalized) - Erythema and edema of hands/feet✋️🦶 • Tx: Aspirin & IVIG • Cx: coronary artery aneurysms, MI🫀 • Poor prognostic factors (Kobayashi score): - Na <=133 - CRP >=10 mg/dL (>=100 mg/L) - Neutrophils >=80% Juvenile Dermatomyositis • Sx: muscle weakness, cutaneous features (Helitrope rash) • Dx: High CK, ANA
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#Immunology Wiskott-Aldrich Syndrome WAS • Genetic condition characterized by impaired T cell function and thrombocytopenia • Mutation in WAS gene 🧬 (X-linked recessive) • Common in boys 👦 • Sx: Triad of: 1. Thrombocytopenia 2. Eczema 3. Recurrent bacterial infections • Dx: ⬆️IgA & IgE X-linked (Bruton) Agammaglobulinemia • X-linked recessive disease causes a complete deficiency of mature B lymphocytes 🧬 • Common in boys👦 • Sx: starts at 3-6 mo after materal IgG starts to decline: - Recurrent severe sinopulmobary and GI infections - Small/absent lymphoid tissues (Tonils, adenoids, LNs) • Dx: Low B Cells (CD19) • Tx: IV immunoglobulins (IVIG)💉
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#Dermatology 🧴 Atopic Dermtitis • Sx: - Infants (<2 y): Itchy, red, scaly, crusted lesions on extensor surfaces, trunk, cheeks, and scalp - Child/adult: lichenified plaques in flexural creases • Mx: topic emollients, steroids • Cx: - Bacterial like S. Aureus (grape-like pattern🍇) - Viral like HSV/eczema herpticup Impetigo Nonbullous • Pathogen: 1. S. Aureus 2. GAS (S. Pyogenes) • Sx: Honey-crusted lesions🍯 • A pt w imptigo 1-2 w with low complement -> Post-strept GN Bullous • Pathogen: S. Aureus • Sx: Rapidly enlarging flaccid bullae w yellow fluid🟡 Tx for Impetigo: - Limited to skin: Topic Abx (Mupirocin) - Extensive: PO Abx (cephalexin or clindamycin) Cat Scratch Disease🐈😼 • Pathogen: Bartonella Henselae • Sx: enlarged LNs • Mx: Macrolides Abx (Azithromycin)
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#Endocrinology 🍰🍭 T1DM: • Autoimmune • Screen for celiac disease at diagnosis, every 2 y • Screen for microvascular cx: after 5 y • Tx: Full bolus insulin regimen w once-daily insulin glargine - Honeymoon period: hypoglycemia attacks when the pt first start insulin DKA • Diagnostic Criteria: - Glucose >200 mg (11.1 mmol) - pH 7.3 - Ketones in urine or serum • Mx: - Fluid & electrolyte tx💦 - Gradual decline in glucose (to minimize the risk of cerebral edema)💦🧠 - Potassium repletion: Hyperkalemia -> K not given Normokalemia -> Give K w insulin Hypokalemia -> Give K before insulin⚠️ - Insulin: regular insulin, continuous infusion of 0.1 U/kg/hr Normal Puberty Female: Onset 8-13 yo 1. Thelarche 2. Pubarche 3. Growth spurt 4. Menarche (mean: 12.5 yo) Male: Onset 9-14 yo 1. Testicular enlargement 2. Penile enlargement 3. Pubarche 4. Growth spurt Approach to precocious puberty Early secondary sexual development: (F <8 yo, M <9 yo) Bone age: 🦴 1. Advanced Bone Age: • Low basal LH -> GnRH stimulation test: - Low LH: Peripheral precocious puberty - High LH: Central precocious puberty (Brain MRI)🧠 • High basal LH: Central precocious puberty (Brain MRI)🧠 2. Normal bone age • Isolated breast development: Premature thelarche (Pelvic US) • Isolated pubic hair development: Premature adrenarche (test DHEA) 💉 Nutritional Rickets (Vit D def) • RF: exclusive breastfeeding 🤱, inadequate sun exposure☀️ • Sx: - Craniotabes (ping-pong skull) - Widening of wrists - Delayed fontanel closure - Frontal bossing - Costochondral joints hypertrophy (Rachitic rosary) - Femoral & tibial bowing • Dx: Labs and Xray Labs: ⬇️Ca, P, Vit D ⬆️Alk Phos, PTH • Mx: Vit D & Ca suppl Familial Short Stature vs Constitutional Growth Delay Family hx Familial: Short stature Constitutional: Delayed puberty Bone age Familial: Normal Constitutional: Less than chronological age
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#Nephrology UTI • RF: - Females - Uncircumcised boys - Fever >=39 - Nitrate - Age <12 mo - Duration >=48 hr - Vesicouretral reflux - Constipation • Sx: Fever, poor feeding, dec urine output • Tx: Mild sx (cystitis): - Oral amoxicillin - TMP/SMX - Nitrofurantoin Unstable UTI or Pyelonephritis: - Inability to tolerate oral -> IV Ceftriaxone, Cefepime, or Ceftaxime • Indications for Imaging: Renal US - First febrile UTI in <2 yo - Recurrent febrile UTI - UTI + Family hx of renal disease, poor growth, or HTN - Not responsive to Abx Voiding Cystourethrogram (look for vesicuretral reflux) - Child <6 mo w recurrent UTI, atypical UTI, or UTI + US showing hydronephrosis - Child 6 mo - 3 yo w atypical UTI or US showing hydronephrosis Renal Scintiography (DMSA scan) - To detect acute pyelonephritis and renal scarring Glomerular Diseases Nephrotic vs Nephritic syndrome Sx: • Nephrotic: generalized edema and peri-orbital edema • Nephritic: HTN Dx: • Protein in 24 h urine: - Nephrotic >3.5 gm - Nephritic <3.5 gm • Urine cast: - Nephrotic: Fatty cast🟡 - Nephrtitic: RBCs cast🔴 • Hyperlipidemia and hypoalbuminemia - Nephrotic: Yes - Nephritic: No Diseases in Pediatrics Nephrotic Syndrome: Minimal change disease - Common in children👧 - Tx: steroid - Confirm remission -> Urine dipstick negative or trace for 3 consecutive days Nephritic Sybdrome: Post-streptococcal glomerulonephritis PSGN - 10 d after the infection - Has Low C3 IgA nephropathy/Burger’s disease - Presents within 3 d of URTI🤧 Alport syndrome - Hearing loss👂❌, ocular : findings👁️, +family hx of ESRD - Cause: defect in collagen type 4 Primary Nocturnal Enuresis • Urinary incontinence in >5 yo • Caused by destrusor overactivity/instability • Dx: >2 times per week for 3 mo in >5 yo patient - Urinalysis to R/O other causes • Mx: - Lifestyle changes (minimize fluid intake before bed, void before bed, reward system like gold star chart) - Enuresis alarm ⏰ - Desmopressin tx • Bed-wetting is Normal behavior until 6 yo Prevent progression of Nephrotic Syndrome -> Enalapril Steroid resistant nephrotic syndrome is the Inability to induce a remission within 4 weeks of daily steroid therapy
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#Hematology 🩸 IDA • Screening for anemia: - W/o risk factors -> At 12 mo - W risk factors (Prematurity, LBW) -> At birth and 4 mo • Primary causes of IDA in pediatrics -> Dietary issues • Exclusively breastfeeding 🤱-> Iron supplements should be given from 4 mo • No cow milk 🐮 in the first year of life • Physiologic anemia: - Term: 2-3 mo - Preterm: 1-2 mo Sickle Cell Anemia • AR, Hallmarks in SCD is Vaso-occlusive phenomena, Hemolytic anemia • Dx: - Markers of hemolysis: high indirect hyperbilirubinemia, LDH, AST, reticulocyte - Peripheral boold film: Sickle cell, Howell-Jolly body, Target cell - Confirm: Hb electrophoresis • Mx: - Hydroxyurea: prevent cx (vaso-occlusive crises) by inc HbF - Vaccines: pneumococcal, meningococcal, Hemophilus influenza type b - Daily pencillin prophylaxis (until 5 y) • Cx: Acute: Painful episode - Triggered by: inf, dehydration, cold weather, high altitude - Site: legs, arms, back - Mx: Regydration & Pain management, If fever: Abx Acute Chest Syndrome ACS - Sx: fever, chest pain, hypoxemia, wheezing, cough, new pulmonary infiltrate - Mx: broad spectrum Abx, Transfusion Aplastic crisis - Arrest of erythropoiesis - Dx: dec reticulocytes, Acute drop of Hb - Organism: Parovirus B-19 Splenic Squestration Crisis - Life-threatening - Dx: Acute drop of Hb typically two below baseline, reticulocytosis Chronic: - Stroke - Renal impairment & HTN - Pigmented gallstones Hereditary Spherocytosis - AD - Family hx of gallbladder stone/Splenectomy - Can presents as neonatal jaundice Dx: - Blood film: Spherocytes - Gold standard: Erosin 5 Malemide (EMA) binding test - Osmotic fragility test - To differentiate from AHA: Coombs test (negative) Tx: - EPO, iron and folate - Splenectomy (curative) Hemophilia (A&B) • A: Vlll, B: lX, X-linked • Sx: - Hemarthrosis (knee) - Intracranial bleeding - IM/Retroperitoneal hematoma - Hematuria, hemospermia • Dx: - Prolonged aPTT - Normal PT, thrombin time, bleeding time Infantile Vitamin K-Deficient Bleeding • Sx: presents at 2-7 d of life, easy bruising, umbilical/mucosal/GI bleeding, Intracranial hemorrhage • Dx: prolonged PT • Tx: - IV vit K - Unstavle -> FFP • Prevention: IM vit K at birth • Vit K dependent factors: II, VII, IX, X (2,7,9,10) Immune Thrombocytopenia Purpra ITP - Superficial bleeding, can be preceded by viral inf - Dx: isolated thrombocytopenia (<100,000) - Tx: Cutaneous sx only -> Observe Bleeding -> CS, IVIG, or Anti-D - Tx in adults: No bleeding, Plt 50,000-30,000 -> No tx Minor bleeding, Plt 50,000-30,000 -> CS (prendnisone) Severe bleeding or Plt less than 10,000 -> IVIG or Anti-Rho (anti-D) Recurrent/Failed -> Splenectomy Thrombotic Thrombocytopenic Purpura TTP • Severe deficiency in ADAMTS13 • Sx: fever, neurological sx • Dx: CBC: - Thrombocytopenia - Low Hb - Film: schistocytes (Microangiopathic hemolytic anemia) Hemolysis: - High reticulocytes - High LDH - Low Haptoglobin Coagulation profile - Normal/mildly prolonged PT, aPTT - Normal/mildly elevated D-dimer Liver chemistry - High indirect bilirubin BMP - High BUN, Cr Urinalysis - Hematuria, proteinuria • Tx: Plasma Exchange Hemolytic Uremic Syndrome HUS • Causes: E. Coli (O157:H7, O104:H4) • Sx: Renal impairment • Dx: - Thrombocytopenia - Film: schistocytes (Microangiopathic hemolytic anemia) - AKI: ⬆️BUN and Cr • Tx: - Typical HUS > Supportive - Atypical HUS > Eculizumab (causes fulminant meningococcal inf, screen for vaccin.) ⚠️Abx are C/I -> Injury to bacterial wall releasing large anounts of toxins!
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#Neurology 🧠 Febrile Siezure🤒 • Siezure + Fever (>=38) in 6 mo-5 yo • Simple vs Complex - Simple (one of the following): <15 min Generalized tonic-clonic No recurrence in 24 hr - Complex (one of the following): >15 min Focal onset Recur in 24 hr • Mx: - If >=5 min: Abortive tx (IV lorazepam) - Antipyretics - Reassurance Rolandic Epilepsy (Benign Epilepsy w Centrotemporal Spikes) • Most common form of benign epilepsy in children • Sx: usually during sleep 😴, facial twitching and numbness • Dx: EEG: Centrotemporal Spikes • Mx: - Anticonvulsants are only recommended in high frequency/severity Infantile Spasms (West Syndrome) • Sx: Multiple neck flexion followed by neck extension • EEG: Very heterogeneous, hypsarrhythmia Tx: ACTH, Steroid Status Epilepticus • Mx: 1. IV lorazepam (given again if no response) or IV/Rectal diazepam or Buccal midazolam 2. IV phenytoin (recurrent in ER > Fosphenytoin) 3. General anesthesia • Absence seizure > Ethosuximide • Generalized epilepsy > Sodium valporate Guillian Barre Syndrome GBS • Sx: - Acute ascending areflexic paralysis and parasthesia - Hx of URTI/GI inf (Cambylobacter jeujeni) • Dx: clinically • Mx: 1. IVIG or 2. Plasma exchange • Excellent prognosis w full recovery ❤️‍🩹 • To monitor ventilatory impairment🫁 -> Bedside measurement of vital capacity Cerebral Palsy • Heterogeneous group of disorders affecting muscle tone and the development of movement and posture, non-progressive • RF: - Birth wt <1.5 kg - Prematurity⚠️ - TORCH infection • Red flags 🚩 Definite hand preference before 1 yo 🚩Persistent moro reflex (>6 mo) • Types: - Spastic (75%): Can result in hemiplagia (one side of the body), diplegia (both legs 🦵), quadriplegia (all limbs) - Dyskinetic/Athentoid (Basal ganglia affected, maybe associated w kernicterus) - Ataxic Duchenne Muscular Dystrophy • Type of Progressive Muscular Dystrophies • X-linked recessive disorder • Screening: Creatinine kinase • Sx: Calf pseudohypertrophy, Grower maneuver (pt supports himself on his thighs and uses his hands to walk up his body until he’s standing)
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#GI 🍜 Celiac Disease • Autoimmune disease causing malabsorption • Sx: Diarrhea, Steatorrhea, Abdominal bloating, N&V, Loss of subcutaneous fat, Dermatological (Dermtitis herpetiformis) • Dx: - Serology: IgA Tissue Transglutaminase Antibody (tTG IgA), or Anti-endomysial antibody (2nd line) - Confirmatory > EGD w Small Intestine Biopsy Eosinophilic Esophagitis • Chronic immune-mediated esophageal inflammation • Associated w Atopy (Asthma, rhinitis, atopic dermtitis) • Sx: Dysphagia (compensated by excessive chewing), reflux, chest pain • Dx: Endoscopy & biopsy • Mx: - First line: PPIs - Second: Topical steroids - Dietary modifications Sandifer Syndrome • Movement disorder characterized by torticollis & arching of the spine • Associated w GERD & Hiatal hernia Lactose intolerance • Dx -> Hydrogen breath test
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