GiT Updates and More

Local complications of liver transplantation

Pouchitis

⭕️ RCT ( randomised control trial): In patients with #IBS , small-intestinal release peppermint oil appears to be a cost-effective treatment although there is uncertainty surrounding the ICER ( The incremental cost-effectiveness ratios). When using abdominal pain responder as outcome measure for the ICER, peppermint oil has a high probability of being cost-effective. The use of peppermint oil, which is a low-cost treatment, can be justified by the modest QALY ( Quality Adjusted Life Years) gains and slightly higher proportion of abdominal pain responders. More research and long-term data are necessary to confirm the cost-effectiveness of peppermint oil.

Rheumatic Fever pathogenesis

Fundic Gland Polyps Biopsies are NOT recommended If FGP have atypical features: • Size >1 cm • Antral location • Ulceration • Unusual appearance -> Biopsies can be considered ESGE 2021 #Endoscopy

AGA Clinical Guideline: Gastric Intestinal Metaplasia

Management of hepatocellular ADENOMAS

/wk

⭕️WHO MIGHT RESPOND BEST TO BISACODYL? 💊defecation disorders with normal colonic transit: may benefit from suppository 💊⬇️HAPCs: may benefit from po 💊Combo therapy with different mechanisms of action may be helpful in patients refractory to monotherapy --------------------- ⭕️ THE Q EVERYONE ASKS: IS IT *SAFE* FOR LONG TERM USE? 💊YES! It is safe for long term use! 💊If long term use, aim for 2-3x/wk (goal: 2-3 💩/ wk) 💊NO evidence of harm (dependence, colon damage, ENS damage, colon cancer) with long term use ------------------- ⭕️ SUMMARY 💊bisacodyl is a prodrug 💊stimulant laxative: dual mechanism of action on gut secretion and motility 💊start with 5mg 💊certain patients may benefit more from po vs pr and vice versa 💊may get additive effect with secretagogues 💊 💊

⭕️The most common cause of severe erectile dysfunction in young men is diabetes with chronic poor glycemic control. They almost always say that they didn't know elevated blood sugar could effect their sex life. There are SO many ways diabetes effects sexual function. Microvascular disease impacts erections. Neuropathy effects arousal, sensation, and even make can make it impossible to ejaculate. Glycemic control can prevent these complications.

#IBD

Dapagliflozin, a highly selective SGLT2-inhibitor, is associated with favorable clinical outcomes among diabetic patients with NAFLD.

Management of variceal bleeding

Management of NON Alcoholic liver disease

Breast cancer metastasis

Differential diagnosis of sore throat

Probiotics can improve the eradication of H. pylori, decrease gastrointestinal symptoms, and decrease side effects of antibiotics (especially diarrhea). https://bit.ly/3CkRdQa

📒In the 2021 issue of the statistics and causes of heart disease and strokes from the American Heart Association; The association put together seven golden tips that summarized in this picture: 💡Avoid smoking. 💡Avoid sedentary life and exercise. 💡maintain your weight. 💡Eat healthy food, and keep whole grains - whole fruits - non-starchy vegetables in your daily food. 💡Maintain the proportion of sugar and reduce simple sugars. 💡Maintain the proportion of fats and avoid high cholesterol and LDL. 💡Maintain blood pressure.

Summary of Irritablw bowel syndrome #ACG2021