pace your MRCP-PACES

*WHO criteria for Polycythemia Vera by courtesy of Dr Toqeer Bhatti.. Thanks a lot dear dr* *Major* Hemoglobin > 16.5 g/dL in men and > 16 g/dL in women, or hematocrit > 49% in men and > 48% in women, or red cell mass > 25% above mean normal predicted value Bone marrow biopsy showing hypercellularity for age with trilineage growth (panmyelosis) including prominent erythroid, granulocytic, and megakaryocytic proliferation with pleomorphic, mature megakaryocytes (differences in size) Presence of JAK2V617F or JAK2 exon 12 mutation The *minor* WHO criterion is as follows: Serum erythropoietin level below the reference range for normal Good luck

*Some possible findings in ploycythemia vera by courtesy of Dr Toqeer Bhatti.. Thanks a lot dear dr* Splenomegaly (75% of patients) Hepatomegaly (30%) Plethora Hypertension Good luck

*Symptoms of polycythemia vera by courtesy of Dr Toqeer Bhatti.. Thanks a lot dear dr* Impaired oxygen delivery due to sludging of blood may lead to the following symptoms: Headache Dizziness Vertigo Tinnitus Visual disturbances Angina pectoris Intermittent claudication Good luck

👉 *IMPORTANT 139* 👈 *Heart and Polyarteritis nodosa* You may find in Polyarteritis nodosa : Small and medium vessel vasculitis Angina Myocardial Infarction Arrhythmias Congestive cardiac Failure Pericarditis Conduction defects. Good luck.

👉 *IMPORTANT 138* 👈 *Heart and Noonan syndrome ( common in some centers )* You may find in Noonan syndrome: Atrial Septal Defect Pulmonary stenosis Good luck.

👉 *IMPORTANT 137* 👈 *Heart and Myotonic dystrophy* You may find in Myotonic dystrophy: Progressive conduction defects arrhythmias LV dysfunction Good luck.

👉 *IMPORTANT 136* 👈 *Heart and Marfan’s syndrome* You may find in Marfan’s syndrome : Mitral valve prolapse Aortic Regurgitation Aortic dissection Good luck.

👉 *IMPORTANT 135* 👈 *Heart and Hypothyroidism* You may find in Hypothyroidism: Sinus bradycardia Low pulse pressure Pericardial effusion High blood pressure Coronary artery disease Low-voltage ECG. Good luck.

👉 *IMPORTANT 134* 👈 *Heart and Haemochromatosis* You may find in Haemochromatosis: AF Cardiomyopathy Good luck.

👉 *IMPORTANT 485* 👈 *Some GIT symptoms important for history taking* Tummy pain (Abdominal pain) Feeling sick (nausea) Heart burn (Reflux) Difficulty swallowing (Dysphagia) Painful swallowing (Odynophagia) Vomiting (Throwing up) How frequent do you open your bowels Lose motions (Diarrhea) Is it easy to flush it down (Steatorrhea) Vomiting of blood (Hematemesis) Bleeding with back passage (Hematochezia) Pain with the back passage Passing black Tarry Offensive motions (Melena) Swollen tummy (Distended abdomen) Yellowish discoloration of the eye white (Jaundice) Change in color of motions; Paller Or Darker. Good Luck

👉 *IMPORTANT 484* 👈 *Some Chest symptoms important for history taking* Chest pain Shortness of breath Coughing Phlegm production (Sputum production) What Color is it? How frequent? Amount? Coughing up blood (Hemoptysis) Noisy chest (wheezing) Sore throat (URTI) Runny nose Snoring (Upper airway obstruction/OSA) Good Luck

👉 *IMPORTANT 483* 👈 *Some Cardiology symptoms important for history taking* Chest pain (Cardiac or non-cardiac) Racing heart (Palpitations) Shortness of breath (Dyspnea) Left side heart failure symptoms (Shortness of breath on lying flat (orthopnea), waking up from sleep short of breath needing to sit up (paroxysmal nocturnal dyspnea) Low Cardiac output symptoms (dizziness , headaches , leg cramps ,black outs or funny turns) Right side heart failure symptoms (pain in tummy (right hypochondrium), swollen legs) Good Luck

Eid mubarik dear coalleagues Please excuse me for Eid holidays,, We will restart after academic activities after eid, Sorry for the inconvenience

ANNOUNCEMENT Hello n salam everyone Regarding our *July 2022 online course ( 9 days ) for PACES MRCP (UK).* starting from *12 July and finishing on 20 July.* There are *Only 2 Active slots available on first come--first served basis.* Listener slot available too. WhatsApp No: 00923346036496. Email: drtanzeelbukhari@gmail.com GOOD LUCK.

👉 *IMPORTANT 136* 👈 *Heart and Marfan’s syndrome* You may find in Marfan’s syndrome : Mitral valve prolapse Aortic Regurgitation Aortic dissection Good luck.

👉 *IMPORTANT 135* 👈 *Heart and Hypothyroidism* You may find in Hypothyroidism: Sinus bradycardia Low pulse pressure Pericardial effusion High blood pressure Coronary artery disease Low-voltage ECG. Good luck.

👉 *IMPORTANT 134* 👈 *Heart and Haemochromatosis* You may find in Haemochromatosis: AF Cardiomyopathy Good luck.

✌️✌️ *HEARTIEST CONGRATULATIONS* ✌️✌️ To *Dr. Maria Syed* For passing *MRCP UK PART 2 (Written)* She has been a keen member of our part 2 group. We wish her the best for her future.

ANNOUNCEMENT Hello n salam everyone Regarding our *July 2022 online course ( 9 days ) for PACES MRCP (UK).* starting from *12 July and finishing on 20 July.* There are *Only 2 Active slots available on first come--first served basis.* Listener slot available too. WhatsApp No: 00923346036496. Email: drtanzeelbukhari@gmail.com GOOD LUCK.

👉 *IMPORTANT 482* 👈 Please remember that the main cause of mortality in ESRD is Cardio-vascular diseases Good Luck