MedPharm || طبصيدلة

Regarding replacement therapy of hypothyroidism. The following statements are true regarding Levothyroxine (L-thyroxine, T4) therapy for patients with hypothyroidism EXCEPT: a-Young patients with long-standing disease and patients older than 45 years without known cardiac disease should be started on 50 mcg daily b- The initial daily dose for older patients with cardiac disease is 25mcg/day titrated upward in increments of 25 mcg at monthly intervals c-The average maintenance dose for most adults is about 125 mcg/day d-Levothyroxine is the drug of choice for pregnant women, it does not need to adjust the dose to maintain free T4 concentrations in the normal range e-Cholestyramine, and dietary fiber supplements may impair the absorption of levothyroxine from the Gl tract

-8.5 is 41 years old male with negative medical history, he presented with palpitation, arxiety, heat intolerance, excessive sweating and mild hair loss, upon examination he had an elevated T3,T4 with undetectable TSH. Ultrasound showed a multinodular goiter. One of the following treatment options may exacerbate the condition of this patient?

-A 60-years-old female with a known history of hypothyroidism present to the emergency department in a stuporous state. She has a low body temperature of 33.5°C, bradycardia, and respiratory depression. Laboratory tests confirmed diagnosis of myxedema coma. What is the appropriate initial treatment for this patient

CC, is a 65-year-old woman who has gained 6 kg of weight over the past year. She also has cardiac problem, fatigue, polyneuropathy, slow speech, constipation, depression, and can't stand the cold. Her skin is pale, cool, dry, and thick. The serum T4 (total) is 3.5 mcg/dL (normal range: 4.5-10.9 mcg/dL), the T3 level is 53 ng/dL (normal range: 60-181 ng/dL), and the blood TSH level is 6.2 mIU/L (normal range: 0.5-4.7 mIU/L). The proper initial treatment for this case will be: