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388
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388
The Fc fragment obtained from Papain digestion is named for its ability to:
A) Bind antigen specifically
B) Crystallize in cold storage
C) Form disulfide bridges
D) Digest bacteria
388
Cleavage of an IgG molecule by Papain produces:
A) One F(ab')₂ fragment and no Fc fragment
B) Two identical Fab fragments and one Fc fragment
C) Four separate protein chains (2 H and 2 L)
D) Two Fc fragments and one Fab fragment
388
The light chains of a single human antibody molecule:
A) Contain both κ and λ chains simultaneously.
B) Are composed of either two κ or two λ chains, never mixed.
C) Are designated as μ, γ, α, δ, or ε.
D) Determine the isotype class of the antibody.
388
The absence of a hinge region in an antibody molecule is compensated for by the presence of:
A) VH domain
B) CL domain
C) CH4 domain
D) Extra disulfide bonds
388
Which cell connects innate immunity to adaptive immunity?
A) Neutrophil
B) Mast cell
C) B lymphocyte
D) Dendritic cell
388
Hereditary angioedema is classically associated with deficiency of:
A) MBL
B) C1 inhibitor
C) C3
D) C5–C9
388
An infant has recurrent bacterial infections, particularly early in life. Which complement deficiency is most likely?
A) C1 inhibitor deficiency
B) MBL deficiency
C) C5 deficiency
D) C9 deficiency
